ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy

G Sgouros, WE Bolch, A Chiti… - Journal of the …, 2021 - journals.sagepub.com
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Dosimetry of internal emitters

G Sgouros - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
Response and toxicity prediction is essential to rational implementation of cancer therapy.
The biologic effects of radionuclide therapy are mediated via a well-defined physical …

Voxel-based mouse and rat models for internal dose calculations

MG Stabin, TE Peterson, GE Holburn… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The ability to estimate absorbed doses in experimental animals to which radiolabeled
material has been administered may be important in explaining and controlling potential …

Mice and the A-bomb: Irradiation systems for realistic exposure scenarios

G Garty, Y Xu, C Elliston, SA Marino… - Radiation …, 2017 - meridian.allenpress.com
Validation of biodosimetry assays is normally performed with acute exposures to uniform
external photon fields. Realistically, exposure to a radiological dispersal device or reactor …

[HTML][HTML] VADER: a variable dose-rate external 137Cs irradiator for internal emitter and low dose rate studies

G Garty, Y Xu, GW Johnson, LB Smilenov… - Scientific Reports, 2020 - nature.com
In the long term, 137Cs is probably the most biologically important agent released in many
accidental (or malicious) radiation disasters. It can enter the food chain, and be consumed …

Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer

J Grawé, J Biko, R Lorenz, C Reiners, H Stopper… - … /Genetic Toxicology and …, 2005 - Elsevier
In the case of accidental radiation exposure, biological dosimetry has an important role.
Previous studies have indicated that the flow cytometric micronucleus (MN) assay in human …

[HTML][HTML] Effects of arbutin on radiation-induced micronuclei in mice bone marrow cells and its definite dose reduction factor

AS Monfared, H Mozdarani… - Iranian Journal of …, 2016 - ncbi.nlm.nih.gov
Background: Interactions of free radicals from ionizing radiation with DNA can induce DNA
damage and lead to mutagenesis and carsinogenesis. With respect to radiation damage to …

DEVELOPMENT AND ESTIMATION OF HUMAN DOSIMETRY OF A NEW 47SC-RISEDRONATE FOR RADIOPHARMACEUTICAL APPLICATION

L Moghaddam-Banaem… - Radiation Protection …, 2022 - academic.oup.com
Abstract Bisphosphonate risedronate (2-(3-pyridinyl)-1-hydroxyethane diphosphonic acid)
was radiolabeled with scandium-47 (47Sc) as potential therapeutic radiopharmaceutical for …

The genotoxic effects in lymphocyte cultures of children treated with radiosynovectomy by using yttrium-90 citrate colloid

C Turkmen, S Ozturk, SN Unal, B Zulfikar… - Cancer biotherapy & …, 2007 - liebertpub.com
The aim of this study was to investigate the genotoxic effect on the peripheral blood
lymphocytes potentially induced by yttrium-90 citrate colloid (Y-90) in children who were …

Development of bone seeker radiopharmaceuticals by Scandium-47 and estimation of human absorbed dose

L Deilami-Nezhad, L Moghaddam-Banaem… - Applied Radiation and …, 2017 - Elsevier
In this study labeling EDTMP (ethylenediamine tetra (methylene phosphonic acid)) and
HEDP (Hydroxyethylidene-1, 1-Diphosphonic Acid) as the carrier ligands with Scandium-47 …