Machine learning in quantitative PET: A review of attenuation correction and low-count image reconstruction methods

T Wang, Y Lei, Y Fu, WJ Curran, T Liu, JA Nye, X Yang - Physica Medica, 2020 - Elsevier
The rapid expansion of machine learning is offering a new wave of opportunities for nuclear
medicine. This paper reviews applications of machine learning for the study of attenuation …

Human positron emission tomography neuroimaging

JM Hooker, RE Carson - Annual review of biomedical …, 2019 - annualreviews.org
Neuroimaging with positron emission tomography (PET) is the most powerful tool for
understanding pharmacology, neurochemistry, and pathology in the living human brain. This …

In vivo characterization and quantification of neurofibrillary tau PET radioligand 18F-MK-6240 in humans from Alzheimer disease dementia to young controls

TJ Betthauser, KA Cody, MD Zammit… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Tau PET imaging has potential for elucidating changes in the deposition of
neuropathological tau aggregates that are occurring during the progression of Alzheimer …

Linearized Reference Tissue Parametric Imaging Methods: Application to [11C]DASB Positron Emission Tomography Studies of the Serotonin Transporter in Human …

M Ichise, JS Liow, JQ Lu, A Takano… - Journal of Cerebral …, 2003 - journals.sagepub.com
The authors developed and applied two new linearized reference tissue models for
parametric images of binding potential (BP) and relative delivery (R 1) for [11C] DASB …

Strategies to improve neuroreceptor parameter estimation by linear regression analysis

M Ichise, H Toyama, RB Innis… - Journal of Cerebral …, 2002 - journals.sagepub.com
In an attempt to improve neuroreceptor distribution volume (V) estimates, the authors
evaluated three alternative linear methods to Logan graphical analysis (GA): GA using total …

Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited

VJ Cunningham, EA Rabiner… - Journal of Cerebral …, 2010 - journals.sagepub.com
Quantitative estimation of neuroreceptor occupancy by exogenous drugs using positron
emission tomography is based on the reduction in the total volume of distribution (VT) of site …

Tracer kinetic modeling in PET

RE Carson - Positron emission tomography: Basic sciences, 2005 - Springer
The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with
modern instrumentation are key components to successful developments in PET. Clever …

Direct reconstruction of kinetic parameter images from dynamic PET data

ME Kamasak, CA Bouman, ED Morris… - IEEE transactions on …, 2005 - ieeexplore.ieee.org
Our goal in this paper is the estimation of kinetic model parameters for each voxel
corresponding to a dense three-dimensional (3-D) positron emission tomography (PET) …

Longitudinal amyloid imaging using 11C-PiB: methodologic considerations

BNM van Berckel, R Ossenkoppele… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Several methods are in use for analyzing 11C-Pittsburgh compound-B (11C-PiB) data. The
objective of this study was to identify the method of choice for measuring longitudinal …

Positron emission tomography compartmental models: a basis pursuit strategy for kinetic modeling

RN Gunn, SR Gunn, FE Turkheimer… - Journal of Cerebral …, 2002 - journals.sagepub.com
A kinetic modeling approach for the quantification of in vivo tracer studies with dynamic
positron emission tomography (PET) is presented. The approach is based on a general …