Thyroid iodide uptake is basic to the clinical applications of radioiodine. Iodide uptake
occurs across the membrane of the thyroid follicular cells through an active transporter …

Thyroid carcinomas are the most frequent endocrine malignancies. Among thyroid
carcinomas the most frequent types are the differentiated forms (follicular, papillary or mixed …

Editor's note: SNMMI and the European Association of Nuclear Medicine periodically define
new standards/guidelines for nuclear medicine practice to help advance the science of …

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues, in …

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
the active transport of iodide in the thyroid gland and a number of extrathyroidal tissues, in …

The sodium iodide symporter (NIS) is responsible for thyroidal, salivary, gastric, intestinal
and mammary iodide uptake. It was first cloned from the rat in 1996 and shortly thereafter …

Preclinical and clinical tomographic imaging systems increasingly are being utilized for non-
invasive imaging of reporter gene products to reveal the distribution of molecular …

Pertechnetate (as 99mTcO4−), 123I−, and 131I− have a long and successful history of use in
the diagnosis and therapy of thyroid cancer, with uptake into thyroid tissue mediated by the …

Active transport of iodide into the thyroid gland is a crucial and rate-limiting step in the
biosynthesis of thyroid hormones that play an important role in the metabolism, growth, and …

Radioiodine therapy, the most effective form of systemic radiotherapy available, is currently
useful only for thyroid cancer because of thyroid-specific expression of the sodium iodide …