Because of obesity, non‐alcoholic fatty liver disease (NAFLD) is becoming increasingly
important. 10% of NAFLD patients develop non‐alcoholic steatohepatitis (NASH), which …

In molecular imaging modalities such as positron emission tomography (PET) or single
photon emission computed tomography (SPECT), parametric imaging is the process of …

We report the safety, biodistribution, and internal radiation dosimetry, in humans with thyroid
cancer, of 18F-tetrafluoroborate (18F-TFB), a novel PET radioligand for imaging the human …

Pulmonary uptake of 18F-FDG assessed with PET has been used to quantify the metabolic
activity of inflammatory cells in the lung. This assessment involves modeling of tracer …

Hepatic steatosis is associated with obesity and insulin resistance. Whether hepatic glucose
utilization rate (glucose phosphorylation rate; MRglu) is increased in steatosis and/or obesity …

Abstract Background Red blood cells (RBCs) labeled with single-photon emitters have been
clinically used for blood-pool imaging. Although some PET tracers have been introduced for …

Background Quantification of the cerebral metabolic rate of glucose (CMRGlu) by dynamic
[18F] FDG PET requires invasive arterial sampling. Alternatives to using an arterial input …

Positron emission tomography is a three-dimensional imaging technique that measures
physiological effects, including metabolism. 18Fluorodeoxyglucose has been extensively …

Introduction Compartmental modelling is an established method of quantifying 18 F-FDG
uptake; however, only recently has it been applied to evaluate pulmonary inflammation …

Physiological quantification of dynamic PET data requires the determination of an input
function, preferably from plasma. A compartmental model relating a parent radiotracer, its …