The advent of modern C–H functionalization chemistries has enabled medicinal chemists to
consider a synthetic strategy, late stage functionalization (LSF), which utilizes the C–H …

The development of late-stage functionalization (LSF) methodologies, particularly C–H
functionalization, has revolutionized the field of organic synthesis. Over the past decade …

The imaging of specific molecular targets that are associated with cancer should allow
earlier diagnosis and better management of oncology patients. Positron emission …

The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …

Background: Imaging techniques have been in widespread use in the scientific community
for more than 3 decades. They facilitate noninvasive, in vivo studies of the human brain in …

Among the several imaging technologies applied to in vivo studies of research animals,
positron emission tomography (PET) is a nuclear imaging technique that permits the spatial …

Simple Summary PD-L1 plays a crucial role in the immune responses against cancer. Only
around 30% of cancer patients respond to an anti-PD-L1 immune checkpoint inhibitor …

Modern imaging techniques enable researchers to observe drug actions and consequences
as they occur and persist in the brains of abusing and addicted individuals. This article …

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic
principles underlying the individualization of patient therapy and contemporary drug …

2-deoxy-2-[18F] fluoro-d-glucose (18FDG) was developed in 1976 in a collaboration
between scientists at the National Institutes of Health, the University of Pennsylvania, and …