The next generation of platinum drugs: targeted Pt (II) agents, nanoparticle delivery, and Pt (IV) prodrugs
TC Johnstone, K Suntharalingam, SJ Lippard - Chemical reviews, 2016 - ACS Publications
The platinum drugs, cisplatin, carboplatin, and oxaliplatin, prevail in the treatment of cancer,
but new platinum agents have been very slow to enter the clinic. Recently, however, there …
but new platinum agents have been very slow to enter the clinic. Recently, however, there …
Molecular imaging of cancer with positron emission tomography
SS Gambhir - Nature Reviews Cancer, 2002 - nature.com
The imaging of specific molecular targets that are associated with cancer should allow
earlier diagnosis and better management of oncology patients. Positron emission …
earlier diagnosis and better management of oncology patients. Positron emission …
Imaging Prostate Cancer: A Multidisciplinary Perspective1
The major goal for prostate cancer imaging in the next decade is more accurate disease
characterization through the synthesis of anatomic, functional, and molecular imaging …
characterization through the synthesis of anatomic, functional, and molecular imaging …
Synthesis and Evaluation of 18F-labeled Choline as an Oncologic Tracer for Positron Emission Tomography: Initial Findings in Prostate Cancer
TR DeGrado, RE Coleman, S Wang, SW Baldwin… - Cancer Research, 2001 - AACR
The up-regulation of rates of choline uptake and phosphorylation in certain malignancies
has motivated the development of positron-labeled choline analogues for noninvasive …
has motivated the development of positron-labeled choline analogues for noninvasive …
PET imaging in oncology
R Bar-Shalom, AY Valdivia, MD Blaufox - Seminars in nuclear medicine, 2000 - Elsevier
The role of positron emission tomography (PET) during the past decade has evolved rapidly
from a pure research tool to a methodology of enormous clinical potential. Perhaps the most …
from a pure research tool to a methodology of enormous clinical potential. Perhaps the most …
Synthesis and evaluation of 18F-labeled choline analogs as oncologic PET tracers
TR DeGrado, SW Baldwin, S Wang… - Journal of Nuclear …, 2001 - Soc Nuclear Med
Elevated levels of choline (trimethyl-2-hydroxyethylammonium) and choline kinase (CK)
activity in neoplasms have motivated the development of positron-labeled choline analogs …
activity in neoplasms have motivated the development of positron-labeled choline analogs …
EUS, PET, and CT scanning for evaluation of pancreatic adenocarcinoma
HR Mertz, P Sechopoulos, D Delbeke… - Gastrointestinal …, 2000 - Elsevier
Background: Preoperative diagnosis of pancreatic adenocarcinoma can be difficult.
Computed tomography (CT) is the standard, noninvasive imaging method for evaluation of …
Computed tomography (CT) is the standard, noninvasive imaging method for evaluation of …
Brain tumour imaging with PET: a comparison between [18F]fluorodopa and [11C]methionine
A Becherer, G Karanikas, M Szabó, G Zettinig… - European journal of …, 2003 - Springer
Imaging of amino acid transport in brain tumours is more sensitive than fluorine-18 2-fluoro-
deoxyglucose positron emission tomography (PET). The most frequently used tracer in this …
deoxyglucose positron emission tomography (PET). The most frequently used tracer in this …
Clinical role of positron emission tomography in oncology
JB Bomanji, DC Costa, PJ Ell - The lancet oncology, 2001 - thelancet.com
Positron emission tomography (PET) is now in routine use in oncology, through the success
of metabolic imaging, mainly with fluorodeoxyglucose (FDG). Clear benefit is obtained with …
of metabolic imaging, mainly with fluorodeoxyglucose (FDG). Clear benefit is obtained with …
Detection of unexpected additional primary malignancies with PET/CT
T Ishimori, PV Patel, RL Wahl - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
This study evaluated the yield of whole-body 18F-FDG PET/CT for the detection of
unexpected 18F-FDG-avid additional primary malignant tumors in patients being evaluated …
unexpected 18F-FDG-avid additional primary malignant tumors in patients being evaluated …