Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides: Focus Review

KA Morgan, SE Rudd, A Noor, PS Donnelly - Chemical Reviews, 2023 - ACS Publications
Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

[HTML][HTML] Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

[HTML][HTML] Production review of accelerator-based medical isotopes

Y Wang, D Chen, R dos Santos Augusto, J Liang, Z Qin… - Molecules, 2022 - mdpi.com
The production of reactor-based medical isotopes is fragile, which has meant supply
shortages from time to time. This paper reviews alternative production methods in the form of …

Safety of yttrium-90 ibritumomab tiuxetan radioimmunotherapy for relapsed low-grade, follicular, or transformed non-Hodgkin's lymphoma

TE Witzig, CA White, LI Gordon… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: Radioimmunotherapy (RIT) with yttrium-90 (90Y)-labeled anti-CD20 antibody (90Y
ibritumomab tiuxetan; Zevalin, IDEC Pharmaceuticals Corporation, San Diego, CA) has a …

Development of Tumor Targeting Bioprobes (111In-Chimeric L6 Monoclonal Antibody Nanoparticles) for Alternating Magnetic Field Cancer Therapy

SJ DeNardo, GL DeNardo, LA Miers, A Natarajan… - Clinical cancer …, 2005 - AACR
Abstract Objectives: 111In-chimeric L6 (ChL6) monoclonal antibody (mAb)–linked iron oxide
nanoparticle (bioprobes) pharmacokinetics, tumor uptake, and the therapeutic effect of …

Peptide receptor radionuclide therapy with 67Cu-CuSarTATE is highly efficacious against a somatostatin-positive neuroendocrine tumor model

C Cullinane, CM Jeffery, PD Roselt… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Peptide receptor radionuclide therapy (PRRT) using radiolabeled octreotate is an effective
treatment for somatostatin receptor 2–expressing neuroendocrine tumors. The diagnostic …

Thermal dosimetry predictive of efficacy of 111In-ChL6 nanoparticle AMF–induced thermoablative therapy for human breast cancer in mice

SJ DeNardo, GL DeNardo, A Natarajan… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Antibody (mAb)-linked iron oxide nanoparticles (bioprobes) provide the opportunity to
develop tumor specific thermal therapy (Rx) for metastatic cancer when inductively heated …

64Cu Treatment Planning and 67Cu Therapy with Radiolabeled [64Cu/67Cu] MeCOSar-Octreotate in Subjects with Unresectable Multifocal Meningioma: Initial …

DL Bailey, KP Willowson, M Harris… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Our aim was to report the use of 64Cu and 67Cu as a theranostic pair of radionuclides in
human subjects. An additional aim was to measure whole-organ dosimetry of 64Cu and …

ARRONAX, a high-energy and high-intensity cyclotron for nuclear medicine

F Haddad, L Ferrer, A Guertin, T Carlier… - European Journal of …, 2008 - Springer
Purpose This study was aimed at establishing a list of radionuclides of interest for nuclear
medicine that can be produced in a high-intensity and high-energy cyclotron. Methods We …