Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide.
Nuclear myocardial perfusion imaging with either single-photon emission computed …

Abstract Purpose of Review The purpose of this review was to summarize current advances
in positron emission tomography (PET) cardiac autonomic nervous system (ANS) imaging …

Monoamine oxidase (MAO) is an integral protein of outer mitochondrial membranes and
occurs in neuronal and nonneuronal cells in the brain and in peripheral organs. It oxidizes …

The autonomic nervous system plays a critical role in the regulation of cardiac function.
Abnormalities of cardiac innervation have been implicated in the pathophysiology of many …

The human cardiac nervous system consists of a sympathetic and a parasympathetic branch
with (–)-norepinephrine and acetylcholine as the respective endogenous neurotransmitters …

Impaired catecholamine handling in the viable infarct border zone may play an important
role in ventricular remodeling and lethal arrhythmia. We sought to get further biologic …

The technique of organ transplantation is well established and after transplantation the
patient might be faced with the problem of nerve regeneration of the transplanted organ …

Heart failure is one of the growing causes of death especially in developed countries due to
longer life expectancy. Although many pharmacological and instrumental therapeutic …

The deuterium labelling of pharmaceuticals is a useful strategy for altering pharmacokinetic
properties, particularly for improving metabolic resistance. The pharmacological effects of …

Browne, TR, Pharmacokinetic equivalence of stable-isotope-la beled and unlabeled drugs.
Phenobarbital in man; JClin Pharmacol, 22, 309-15 (1982). Burm, AGL, Pharmacokinetics of …