The rapid recognition of intravenously injected colloidal carriers, such as liposomes and
polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development …

The integration of nuclear imaging with nanomedicine is a powerful tool for efficient
development and clinical translation of liposomal drug delivery systems. Furthermore, it may …

A great challenge to clinical development is the delivery of chemotherapeutic agents, known
to cause severe toxic effects, directly to diseased sites which increase the therapeutic index …

Invasive aspergillosis has been studied in laboratory by the means of plethora of distinct
animal models. They were developed to address pathophysiology, therapy, diagnosis, or …

Liposomes have been investigated extensively as carriers for drugs in attempts to achieve
selective deposition and/or reduced toxicity. Liposomes radiolabeled with gamma emitters …

Liposomes are considered as potential carriers for biologically active compounds. One
evident drawback of 'classical'liposomes is their fast elimination by cells of the mononuclear …

Antimicrobial agents may interact synergistically. But to ensure synergy in vivo, the drugs
should both be present at the site of infection at sufficiently high concentrations for an …

Purpose. To gain insight into the host factors influencing liposome localization at sites of
bacterial infection. Methods. In a unilateral Klebsiella pneumoniae pneumonia rat model …

Recent studies with PEG liposomes in patients have consistently shown that liposomes can
induce side effects (flushing, tightness of the chest). Furthermore, the blood clearance of …

Over the last forty years, a small group of commercial radiopharmaceuticals have found their
way into routine medical use, for the diagnostic imaging of patients with infection or …