The correlative triad among aging, dopamine, and cognition: current status and future prospects
The brain neuronal systems defined by the neurotransmitter dopamine (DA) have since long
a recognized role in the regulation of motor functions. More recently, converging evidence …
a recognized role in the regulation of motor functions. More recently, converging evidence …
Parkinson's disease as a result of aging
M Rodriguez, C Rodriguez‐Sabate, I Morales… - Aging cell, 2015 - Wiley Online Library
It is generally considered that Parkinson's disease is induced by specific agents that
degenerate a clearly defined population of dopaminergic neurons. Data commented in this …
degenerate a clearly defined population of dopaminergic neurons. Data commented in this …
Age-related alterations in default mode network: impact on working memory performance
The default mode network (DMN) is a set of functionally connected brain regions which
shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows …
shows deactivation (task-induced deactivation, TID) during a cognitive task. Evidence shows …
Striatal dopamine transporters and cognitive functioning in healthy men and women
LH Mozley, RC Gur, PD Mozley… - American Journal of …, 2001 - Am Psychiatric Assoc
OBJECTIVE: There is growing interest in distinguishing the biological bases of sex
differences in behavior from environmental influences. Sex hormone levels seem to be …
differences in behavior from environmental influences. Sex hormone levels seem to be …
Effect of age and gender on dopamine transporter imaging with [123I]FP-CIT SPET in healthy volunteers
J Lavalaye, J Booij, L Reneman, JBA Habraken… - European journal of …, 2000 - Springer
Dopamine transporter imaging is a valuable tool to investigate the integrity of the
dopaminergic neurons. To date, several reports have shown an age-associated decline in …
dopaminergic neurons. To date, several reports have shown an age-associated decline in …
The role of the striatal dopamine transporter in cognitive aging
N Erixon-Lindroth, L Farde, TBR Wahlin… - Psychiatry Research …, 2005 - Elsevier
We examined the relationship of age-related losses of striatal dopamine transporter (DAT)
density to age-related deficits in episodic memory and executive functioning in a group of …
density to age-related deficits in episodic memory and executive functioning in a group of …
Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment
S Dresel, J Krause, KH Krause, C LaFougere… - European journal of …, 2000 - Springer
Involvement of the dopaminergic system has been suggested in patients suffering from
attention deficit hyperactivity disorder (ADHD) since the symptoms can be successfully …
attention deficit hyperactivity disorder (ADHD) since the symptoms can be successfully …
[HTML][HTML] Drugs of abuse and the aging brain
GJ Dowling, SRB Weiss, TP Condon - Neuropsychopharmacology, 2008 - nature.com
Substance abuse among older adults has received little attention in the past, presumably
because this population has traditionally accounted for only a small percentage of the drug …
because this population has traditionally accounted for only a small percentage of the drug …
Marked disparity between age‐related changes in dopamine and other presynaptic dopaminergic markers in human striatum
JW Haycock, L Becker, L Ang… - Journal of …, 2003 - Wiley Online Library
Because age‐related changes in brain dopaminergic innervation are assumed to influence
human disorders involving dopamine (DA), we measured the levels of several presynpatic …
human disorders involving dopamine (DA), we measured the levels of several presynpatic …
Evaluation of early-stage Parkinson's disease with 99mTc-TRODAT-1 imaging
WS Huang, SZ Lin, JC Lin, SP Wey… - Journal of Nuclear …, 2001 - Soc Nuclear Med
Parkinson's disease is a progressive neurodegenerative disorder characterized by a
selective loss of dopamine in the striatum. Problems remain in the accurate diagnosis of …
selective loss of dopamine in the striatum. Problems remain in the accurate diagnosis of …