Pediatric adrenocortical carcinoma is a rare and potentially fatal disease. In contrast to tumor
in adults, most pediatric adrenocortical carcinomas are functional. Despite the dramatic …

The 2 main causes of primary aldosteronism (PA) are aldosterone-producing adenoma
(APA) and idiopathic adrenal hyperplasia (IAH). Dexamethasone-suppression 131I-6β …

Primary aldosteronism (PA) is the most common cause of endocrine hypertension; it has
been reported in more than 11% of referred hypertensive patients. PA may be caused by …

The aim of this study was to evaluate the role of radionuclide imaging in the characterization
of nonhypersecreting adrenal masses. Methods: A total of 54 patients (19 men, 35 women; …

Context: Imaging with [123I] iodometomidate ([123I] IMTO) has been shown to diagnose
adrenocortical lesions with high sensitivity and specificity. Objective: Our objective was to …

Purpose Somatic KCNJ5 mutation occurs in half of unilateral primary aldosteronism (PA)
and is associated with more severe phenotype. Mutation status can only be identified by …

Purpose: The purpose of this article is to present our initial experience with hypersecretory
adrenal syndromes investigated with radioiodinated I-6-B-iodomethyl-19-norcholesterol (NP …

Background and Aims: Differentiation between the two major subgroups of primary
aldosteronism, bilateral hyperplasia and aldosterone producing adenoma is essential since …

Purpose Primary aldosteronism (PA), characterized by an excessive production of
aldosterone, affects 5− 13% of patients with hypertension. Accurate strategies are needed …

The goal of this study was to evaluate the clinical reliability of the 131I-6β-iodomethyl-
norcholesterol (131I-NP-59) uptake semiquantitative evaluation method we propose for the …