Systematic review: cardiovascular safety profile of 5‐HT4 agonists developed for gastrointestinal disorders

J Tack, M Camilleri, L Chang, WD Chey… - Alimentary …, 2012 - Wiley Online Library
Background The nonselective 5‐HT 4 receptor agonists, cisapride and tegaserod have been
associated with cardiovascular adverse events (AEs). Aim To perform a systematic review of …

Mechanisms of gastroesophageal reflux and gastroesophageal reflux disease

Y Vandenplas, E Hassall - Journal of pediatric gastroenterology …, 2002 - journals.lww.com
Gastroesophageal reflux is a physiological phenomenon, occurring with different severity
and duration in different individuals. Reflux disease occurs when this normal event results in …

Cisapride: what can we learn from the rise and fall of a prokinetic?

EMM Quigley - Journal of digestive diseases, 2011 - Wiley Online Library
Cisapride, the prototype serotonergic agent, evolved from a body of research that defined
the key roles of serotonergic receptors in gastrointestinal motor and sensory function …

Decreased salivary function in patients with end-stage renal disease requiring hemodialysis

CH Kao, JF Hsieh, SC Tsai, YJ Ho… - American journal of kidney …, 2000 - Elsevier
It has been speculated that impaired salivary flow is common in patients with end-stage
renal disease (ESRD) requiring hemodialysis (HD). The aim of this study is to investigate the …

The effect of mosapride on oesophageal motor function and acid reflux in patients with gastro-oesophageal reflux disease

M Ruth, C Finizia, L Cange… - European journal of …, 2003 - journals.lww.com
Objective To evaluate the efficiency of the 5-HT 4 agonist and 5-HT 3 antagonist mosapride,
as compared with cisapride, on oesophageal acid reflux variables and oesophageal motor …

Impaired salivary function in patients with noninsulin-dependent diabetes mellitus with xerostomia

CC Lin, SS Sun, A Kao, CC Lee - Journal of Diabetes and its …, 2002 - Elsevier
To test this hypothesis, salivary function was measured by quantitative salivary scintigraphy
in noninsulin-dependent diabetes mellitus (NIDDM) patients, as well as in age-and sex …

[HTML][HTML] Comportamento da mecânica pulmonar após a aplicação de protocolo de fisioterapia respiratória e aspiração traqueal em pacientes com ventilação …

FK Rosa, CA Roese, A Savi, AS Dias… - Revista Brasileira de …, 2007 - SciELO Brasil
JUSTIFICATIVA E OBJETIVOS: A fisioterapia respiratória (FR) em pacientes submetidos a
suporte ventilatório invasivo, atua diretamente no sistema ventilatório podendo alterar a …

Effects of gender and age on the quantitative parameters of [99mTc] pertechnetate salivary gland scintigraphy in normal subjects

F FIrat, TF Çermik, A SarIkaya… - Nuclear medicine …, 2006 - journals.lww.com
Aim To assess the effect of gender and age on [99m Tc] pertechnetate salivary gland
scintigraphy (SGS) in healthy subjects. Methods The study population consisted of 93 …

The effect of cisapride on oesophageal motility and lower sphincter function in patients with gastro-oesophageal reflux disease

C Finizia, L Lundell, L Cange… - European journal of …, 2002 - journals.lww.com
Objectives To evaluate the efficiency by which the 5-HT 4 agonist cisapride affects important
motor functions involved in the control of gastro-oesophageal reflux. Method Thirty patients …

[HTML][HTML] Correlação do pH e volume salivares com sintomas laringofaríngeos

HO Costa, CA Eckley - Revista Brasileira de Otorrinolaringologia, 2004 - SciELO Brasil
Apesar do grande entusiasmo despertado pelo avanço dos conceitos definidores do
conjunto sintomático denominado refluxo laringofaríngeo (RLF), ainda é muito difícil, para o …