Over the past 40 years, a small and highly committed group of scientists has pursued
various investigations focused on understanding the physical phenomena underlying the …

Abstract Sedelnikova, OA, Rogakou, EP, Panyutin, IG and Bonner, WM Quantitative
Detection of 125IdU-Induced DNA Double-Strand Breaks with γ-H2AX Antibody. Radiat …

Radionuclide decay by electron capture and/or internal conversion is accompanied by
complex atomic vacancy cascades and emission of low-energy electrons, resulting in a …

Although the general radiobiologic principles underlying external beam therapy and
radionuclide therapy are similar, significant differences in the biophysical and radiobiologic …

Oncology Book of 2011, British Medical Association's Medical Book Awards Awarded first
prize in the Oncology category at the 2011 BMA Medical Book Awards, Monoclonal Antibody …

Radiation-induced DNA double-strand breaks (DSBs) are critical cytotoxic lesions that are
typically repaired by nonhomologous end joining (NHEJ) in human cells. Our previous work …

Targeted tumor radiotherapy is selectively delivery of curative doses of radiation to
malignant sites. The aim of the targeted tumor radiotherapy is to use the radionuclides which …

Radiation lethality is largely attributed to radiation-induced DNA double-strand breaks
(DSBs). A range of structural complexity is predicted for radiation-induced DSBs. However …

Purpose: The efficacy of DNA-targeting radionuclide therapies might be strongly enhanced
by employing short range particle-emitters. However, the gain of effectiveness is not yet well …

Abstract Datta, K., Jaruga, P., Dizdaroglu, M., Neumann, RD and Winters, TA Molecular
Analysis of Base Damage Clustering Associated with a Site-Specific Radiation-Induced …