A single mutation of SCN5A can lead to several phenotypes in the same family or in a single
patient, such as BrS, long-QT-syndrome type 3, sick sinus syndrome, and a variable degree …

Autonomic innervation plays an important role in proper functioning of the cardiovascular
system. Altered cardiac sympathetic function is present in a variety of diseases, and can be …

Background—Patients with Brugada syndrome present with characteristic ECG
abnormalities (atypical right bundle-branch block and ST-segment elevation) and life …

Background—Although both 123I-metaiodobenzylguanidine (123I-MIBG) imaging and 11C-
hydroxyephedrine (11C-HED) positron emission tomography (PET) are used for assessing …

We present an unusual case of a young Thai immigrant, symptomatic, who had suffered
prior episodes of syncope with strong family background: male, first-degree relatives …

Centuries of inbreeding the domestic dog has resulted in numerous spontaneous breed-
specific and familial diseases of all body systems. Although few animal models of …

To evaluate the presence and extent of global and regional distributions of cardiac
sympathetic dysinnervation in Type 2 diabetes mellitus I-123-metaiodobenzylguanidine (I …

Widely established compared to myocardial perfusion imaging, cardiac autonomous
nervous system (CANS) assessment by radiopharmaceutical means is of potential use …

Aims Risk-stratification of asymptomatic Brugada Syndrome (BS) patients remains a key-
issue. A typical spontaneous BS-ECG pattern and ventricular tachycardia (VT)/ventricular …

Background—German shepherd dogs with inherited arrhythmias and sudden death appear
to be a model for catecholamine-dependent ventricular tachycardias in human subjects. We …