Basics and principles of radiopharmaceuticals for PET/CT

W Wadsak, M Mitterhauser - European journal of radiology, 2010 - Elsevier
The presented review provides general background on PET radiopharmaceuticals for
oncological applications. Special emphasis is put on radiopharmacological, radiochemical …

Update on biology and genomics of adrenocortical carcinomas: rationale for emerging therapies

AM Lerario, DR Mohan, GD Hammer - Endocrine Reviews, 2022 - academic.oup.com
The adrenal glands are paired endocrine organs that produce steroid hormones and
catecholamines required for life. Adrenocortical carcinoma (ACC) is a rare and often fatal …

[HTML][HTML] [11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial

X Wu, R Senanayake, E Goodchild, WA Bashari… - Nature Medicine, 2023 - nature.com
Primary aldosteronism (PA) due to a unilateral aldosterone-producing adenoma is a
common cause of hypertension. This can be cured, or greatly improved, by adrenal surgery …

Evaluation of the Sensitivity and Specificity of 11C-Metomidate Positron Emission Tomography (PET)-CT for Lateralizing Aldosterone Secretion by Conn's Adenomas

TJ Burton, IS Mackenzie, K Balan, B Koo… - The Journal of …, 2012 - academic.oup.com
Context: Identification of unilateral aldosterone-producing (Conn's) adenomas has
traditionally required lateralization by the invasive and technically difficult procedure of …

Functional imaging with 11C-metomidate PET for subtype diagnosis in primary aldosteronism

M Soinio, AK Luukkonen, M Seppänen… - European journal of …, 2020 - academic.oup.com
Abstract Objective Endocrine Society guidelines recommend adrenal venous sampling
(AVS) in primary aldosteronism (PA) if adrenalectomy is considered. We tested whether …

Aldosterone synthase inhibitors for cardiovascular diseases: a comprehensive review of preclinical, clinical and in silico data

L Lenzini, G Zanotti, M Bonchio, GP Rossi - Pharmacological research, 2021 - Elsevier
Aldosterone, the main mineralocorticoid hormone, plays a fundamental role in maintaining
blood pressure (BP) and volume under hypovolemic conditions. However, in numerous …

PET imaging of adrenal cortical tumors with the 11 (beta)-hydroxylase tracer (11) C-metomidate

M Bergstrom, C Juhlin, TA Bonasera… - The Journal of …, 2000 - search.proquest.com
ll B—Hydroxylase Tracer 11C-Metomidate Page 1 PET Imaging of Adrenal Cortical Tumors with
the ll B—Hydroxylase Tracer 11C-Metomidate Mats Bergstrom, Claes Juhlin. Thomas A …

Functional imaging of endocrine tumors: role of positron emission tomography

K Pacak, G Eisenhofer, DS Goldstein - Endocrine Reviews, 2004 - academic.oup.com
This article provides an update on functional imaging approaches for diagnostic localization
of endocrine tumors, with emphasis on positron emission tomography (PET).[18F] …

Diagnosis and management of adrenal incidentalomas

L Barzon, M Boscaro - The Journal of urology, 2000 - Elsevier
PURPOSE: The incidental discovery of adrenal masses has become a common clinical
problem. We address current trends in clinical, endocrine, radiological and scintigraphic …

[HTML][HTML] First-in-human evaluation of [18F]CETO: a novel tracer for adrenocortical tumours

I Silins, A Sundin, M Lubberink, L O'Sullivan… - European Journal of …, 2023 - Springer
Purpose [11C] Metomidate positron emission tomography (PET) is currently used for staging
of adrenocortical carcinoma and for lateralization in primary aldosteronism (PA). Due to the …