Quantitative 18 F-FDG PET is increasingly being recognized as an important tool for
diagnosis, determination of prognosis, and response monitoring in oncology. However, PET …

Osteosarcoma is the most common primary malignancy of bone in children and young
adults. This tumor has a very heterogeneous genetic profile and lacks any consistent …

Tumors have a greater reliance on anaerobic glycolysis for energy production than normal
tissues. We developed a noninvasive method for imaging glucose uptake in vivo that is …

Osteosarcoma is a malignant tumor that primarily affects the long bones but can also involve
other bones in the body. It has a bimodal distribution with peaks in the second decade of life …

“Functional” tumor treatment response parameters have been developed to measure
treatment induced biochemical changes in the entire tumor mass, using positron emission …

Standardized uptake value (SUV) for [F-18] fluorodeoxyglucose (FDG) studies that is
commonly used to differentiate malignant from benign tumors and to assess the efficacy of …

Positron emission tomography (PET) is the most powerful molecular imaging technique
currently available for clinical use. Because deranged tumour metabolism is a common …

Tumor proliferation has prognostic value in resected early-stage non-small cell lung cancer
(NSCLC). We evaluated whether [F-18] fluorodeoxyglucose (FDG) uptake of NSCLC …

Background: Sarcomas represent a significant diagnostic and therapeutic challenge that
requires techniques to provide better assessment of the disease than provided by traditional …

Sarcomas—like leukemias, which are also mesodermal malignancies—carry biological
significance disproportionate to their clinical frequency. Identification of mutations and …