Myocardial viability assessment using nuclear imaging

I Matsunari, J Taki, K Nakajima, N Tonami… - Annals of nuclear …, 2003 - Springer
Myocardial assessment continues to be an issue in patients with coronary artery disease
and left ventricular dysfunction. Nuclear imaging has long played an important role in this …

Association between abnormal myocardial fatty acid metabolism and cardiac-derived death among patients undergoing hemodialysis: results from a cohort study in …

M Moroi, N Tamaki, M Nishimura, K Haze… - American journal of …, 2013 - Elsevier
BACKGROUND: Detecting myocardial ischemia in hemodialysis patients is crucial given the
high incidence of silent ischemia and the high cardiovascular mortality rates. Abnormal …

Metabolic imaging using SPECT

J Taki, I Matsunari - European Journal of Nuclear Medicine and Molecular …, 2007 - Springer
Introduction In normal condition, the heart obtains more than two-thirds of its energy from the
oxidative metabolism of long chain fatty acids, although a wide variety of substrates such as …

[PDF][PDF] 123I-BMIPP fatty acid analogue imaging is a novel diagnostic and prognostic approach following acute myocardial infarction

SK Biswas, M Sarai, H Hishida… - Singapore medical …, 2009 - researchgate.net
Fatty acid oxidation is the most efficient mode of myocardial energy production which
requires a large amount of oxygen. Thus, alteration of fatty acid oxidation is considered to be …

Comparison of baseline and low-dose dobutamine technetium-99m sestamibi scintigraphy with low-dose dobutamine echocardiography for predicting functional …

M Leoncini, G Marcucci, R Sciagrą… - The American journal of …, 2000 - Elsevier
Injection of sestamibi during low-dose dobutamine (LDD) infusion might improve tracer
ability to detect viable myocardium. This study investigated the potential value of LDD …

Cardiac event risk stratification in patients with end-stage renal disease: Sub-analysis of the B-SAFE study

K Zen, N Tamaki, M Nishimura, E Nakatani… - International Journal of …, 2016 - Elsevier
Background The aim of this study was to investigate whether 123I-labelled β-methyl
iodophenyl–pentadecanoic acid (BMIPP) imaging as an abnormal myocardial fatty acid …

Comparative study of dobutamine stress echocardiography and dual single-photon emission computed tomography (thallium-201 and I-123 BMIPP) for assessing …

N Yasugi, S Koyanagi, K Ohzono, K Sakai… - Circulation …, 2002 - jstage.jst.go.jp
Discordance between the 123I-labelled 15-iodophenyl-3-R, S-methyl pentadecanoic acid
(BMIPP) and 201Tl findings may indicate myocardial viability (MV). This study compared …

Reduced 123I-BMIPP uptake implies decreased myocardial flow reserve in patients with chronic stable angina

H Kageyama, K Morita, C Katoh, T Tsukamoto… - European journal of …, 2006 - Springer
Purpose Long-chain fatty acid (LCFA) is the main energy source for normal myocardium at
rest, but in ischemic myocardium, the main energy substrate shifts from LCFA to glucose …

Future directions of myocardial fatty acid imaging

CJ Pastore, JW Babich, JE Udelson - Journal of nuclear cardiology, 2007 - Springer
The hierarchy of cardiac fuel consumption forms the basis of fatty acid (FA) imaging of the
myocardium in acute and chronic ischemic heart disease. FAs are the predominant (70 …

The Japanese experience with metabolic imaging in the clinical setting

N Tamaki, K Morita, Y Kawai - Journal of nuclear cardiology, 2007 - Springer
Conclusions Reduced utilization of fatty acids at rest often is observed in severely ischemic
myocardium and possibly postischemic myocardium despite normal perfusion at rest. The …