Malignant cells are known to have accelerated metabolism, high glucose requirements, and
increased glucose uptake. Transport of glucose across the plasma membrane of …

Tumor cells have an increased demand for nutrients; this demand is met by increased
availability of nutrients through vasculogenesis and by enhanced cellular entry of nutrients …

Glucose is the major energy source for mammalian cells as well as an important substrate
for protein and lipid synthesis. Mammalian cells take up glucose from extracellular fluid into …

Breast cancer is characterized by elevated glucose consumption resulting in increased
uptake of 18F-FDG. However, tracer uptake varies considerably among tumors imaged with …

Metabolic reprogramming and altered bioenergetics have emerged as hallmarks of cancer
and an area of active basic and translational cancer research. Drastically upregulated …

Abstract Glucose transporter 1 (GLUT1), the uniporter protein encoded by the SLC2A1 gene,
is a key rate-limiting factor in the transport of glucose in cancer cells, and frequently …

Abstract Purpose: The transcription factor Forkhead box protein M1 (FOXM1) plays critical
roles in cancer development and progression. However, the regulatory role and underlying …

Although FDG uptake is closely related to the expression of the glucose transporter (GLUT)
in malignant tumors, such a relationship has not been fully investigated in inflammatory …

Background Non-optimal weather conditions and air pollution pose a significant threat to
children's health. However, the relative impact of different environmental exposures on …

Glucose, a major source of energy for all cells, is transported into cells with the help of
glucose transporters (GLUTs). These transporters are of two types, namely sodium …