Abstract Background Auger electrons (AEs) are very low energy electrons that are emitted
by radionuclides that decay by electron capture (eg 111 In, 67 Ga, 99m Tc, 195m Pt, 125 I …

Over the past 40 years, a small and highly committed group of scientists has pursued
various investigations focused on understanding the physical phenomena underlying the …

Auger-electron emitters represent an attractive alternative to beta-particle emitters for cancer
therapy if they can be placed intracellularly, especially in close proximity to (or within) …

The purpose of the present study was to evaluate both in vitro and in vivo a series of boron-
containing nucleosides that potentially could be used as delivery agents for neutron capture …

Radionuclide decay by electron capture and/or internal conversion is accompanied by
complex atomic vacancy cascades and emission of low-energy electrons, resulting in a …

Targeted radionuclide therapy using Auger electrons is a promising strategy in cancer
treatment. A DNA-binding Hoechst-tagged radioiodinated BODIPY derivative ([125I] BH) has …

Purpose: Neoplastic meningitis is often the final outcome of disseminated cancer and is
rapidly lethal. Its limited treatment relies on systemic or intrathecal chemotherapy with …

The relatively high linear energy transfer of Auger electrons, which can cause clustered DNA
damage and hence efficient cell death, makes Auger emitters excellent candidates for …

The Auger electron emitting agent 5-[125 I] iodo-2′-deoxyuridine (ie [125 I] IUdR) holds
promise for the treatment of residual glioma after surgery because this thymidine analogue …

In Vivo Therapy of Neoplastic Meningitis with Methotrexate and 5-[¹²⁵I]iodo-2'-deoxyuridine
Page 1 In Vivo Therapy of Neoplastic Meningitis with Methotrexate and 5-[125I]iodo-2Æ-deoxyuridine …