Lipid nanoparticles─ from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement
R Tenchov, R Bird, AE Curtze, Q Zhou - ACS nano, 2021 - ACS Publications
Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …
vehicles to deliver a variety of therapeutics. Currently in the spotlight as vital components of …
[HTML][HTML] Liposomes: clinical applications and potential for image-guided drug delivery
N Lamichhane, TS Udayakumar, WD D'Souza… - Molecules, 2018 - mdpi.com
Liposomes have been extensively studied and are used in the treatment of several
diseases. Liposomes improve the therapeutic efficacy by enhancing drug absorption while …
diseases. Liposomes improve the therapeutic efficacy by enhancing drug absorption while …
Nanoparticle approaches against bacterial infections
W Gao, S Thamphiwatana… - Wiley interdisciplinary …, 2014 - Wiley Online Library
Despite the wide success of antibiotics, the treatment of bacterial infections still faces
significant challenges, particularly the emergence of antibiotic resistance. As a result …
significant challenges, particularly the emergence of antibiotic resistance. As a result …
Lipid‐based nanotherapeutics for siRNA delivery
A Schroeder, CG Levins, C Cortez… - Journal of internal …, 2010 - Wiley Online Library
RNA interference (RNAi) is a specific gene‐silencing mechanism triggered by small
interfering RNA (siRNA). The application of RNAi in the clinic requires the development of …
interfering RNA (siRNA). The application of RNAi in the clinic requires the development of …
Ultrasound, liposomes, and drug delivery: principles for using ultrasound to control the release of drugs from liposomes
Ultrasound is used in many medical applications, such as imaging, blood flow analysis,
dentistry, liposuction, tumor and fibroid ablation, and kidney stone disruption. In the past, low …
dentistry, liposuction, tumor and fibroid ablation, and kidney stone disruption. In the past, low …
The enhanced permeability retention effect: a new paradigm for drug targeting in infection
EA Azzopardi, EL Ferguson… - Journal of Antimicrobial …, 2013 - academic.oup.com
Multidrug-resistant, Gram-negative infection is a major global determinant of morbidity,
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …
mortality and cost of care. The advent of nanomedicine has enabled tailored engineering of …
Technetium‐99m radiochemistry for pharmaceutical applications
D Papagiannopoulou - Journal of Labelled Compounds and …, 2017 - Wiley Online Library
Technetium‐99m (99mTc) is a widely used radionuclide, and the development of 99mTc
imaging agents continues to be in demand. This overview discusses basic principles of …
imaging agents continues to be in demand. This overview discusses basic principles of …
Liposomes: quo vadis?
G Storm, DJA Crommelin - Pharmaceutical Science & Technology Today, 1998 - Elsevier
Liposomes have matured as a delivery system for therapeutic agents. It has taken two
decades to develop the liposome carrier concept to a pharmaceutical product level, but …
decades to develop the liposome carrier concept to a pharmaceutical product level, but …
Advantages of liposomal delivery systems for anthracyclines
TM Allen, FJ Martin - Seminars in oncology, 2004 - Elsevier
Liposomes, closed vesicular structures consisting of one or more lipid bilayers, have
generated a great deal of interest as drug delivery vehicles. In particular, they have been …
generated a great deal of interest as drug delivery vehicles. In particular, they have been …
Superoxide dismutase administration, a potential therapy against oxidative stress related diseases: several routes of supplementation and proposal of an original …
J Carillon, JM Rouanet, JP Cristol, R Brion - Pharmaceutical research, 2013 - Springer
Oxidative stress, involved in many diseases, is defined as an impaired balance between
reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes …
reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes …