Purpose Transport of the hepatobiliary scintigraphy agent Tc-99m mebrofenin (MEB) was
characterized and simulation studies were conducted to examine the effects of altered …

Objectives Changes in the expression of hepatocyte membrane transporters in advanced
fibrosis decrease the hepatic transport function of organic anions. The aim of our study was …

Diagnostic imaging of the liver by ultrasound, computed tomography (CT) and magnetic
resonance tomography (MRT) is generally limited to the visualization of the morphology. In …

Abstract Technetium-99m (99m Tc) mebrofenin hepatobiliary scintigraphy (HBS) enables a
quantitative assessment of liver function. This is normally performed in a fasting state and …

The quantitative relationship between changes in portal vein pressure and the perfusion
index was studied, and hepatocellular function was evaluated. A modified protocol of …

The kinetics of organic anions are well described and back-diffusion from hepatocyte to
plasma is accepted. Although iminodiacetic (IDA) analogues, as organic anions, should also …

Halothane and its metabolites cause liver damage by decreasing liver blood flow and
generating free-radical species. Catechin suppresses lipid peroxidation and increases …

Liver ischaemia may lead to parenchymal damage depending on the duration of the
ischaemia. Dimethylsulphoxide (DMSO), a well-known radical oxygen scavenger, is a …

Рассмотрены особенности камерного моделирования и разработана математическая
модель кинетики радиофармацевтических препаратов в организме человека при …