[HTML][HTML] Regional cerebral blood flow in mild cognitive impairment and Alzheimer's disease measured with arterial spin labeling magnetic resonance imaging

A Sierra-Marcos - International journal of Alzheimer's disease, 2017 - hindawi.com
Alzheimer's disease (AD) depicts dynamic changes in regional brain function from early
stages of the disease. Arterial spin labeling-(ASL-) based MRI methods have been applied …

Hippocampal hyperperfusion in Alzheimer's disease

DC Alsop, M Casement, C de Bazelaire, T Fong… - Neuroimage, 2008 - Elsevier
Many of the regions with the earliest atrophy in Alzheimer's Disease (AD) do not show
prominent deficits on functional imaging studies of flow or metabolism. This paradox may …

Perfusion imaging with a freely diffusible hyperpolarized contrast agent

AK Grant, E Vinogradov, X Wang… - Magnetic resonance …, 2011 - Wiley Online Library
Contrast agents that can diffuse freely into or within tissue have numerous attractive features
for perfusion imaging. Here we present preliminary data illustrating the suitability of …

Brain perfusion SPECT: age-and sex-related effects correlated with voxel-based morphometric findings in healthy adults

KJ Van Laere, RA Dierckx - Radiology, 2001 - pubs.rsna.org
PURPOSE: To investigate brain perfusion at single photon emission computed tomography
(SPECT) as a function of age and sex in healthy adult volunteers and to correlate perfusion …

Comparison of relative cerebral blood flow maps using pseudo‐continuous arterial spin labeling and single photon emission computed tomography

P Liu, J Uh, MD Devous, B Adinoff, H Lu - NMR in Biomedicine, 2012 - Wiley Online Library
Pseudo‐continuous arterial spin labeling (PCASL) MRI is a relatively new arterial spin
labeling technique and has the potential to extend the cerebral blood flow (CBF) …

Measurement of cerebral blood flow using graph plot analysis and I-123 iodoamphetamine

K Okamoto, Y Ushijima, C Okuyama… - Clinical nuclear …, 2002 - journals.lww.com
Purpose N-isopropyl-p [I-123] iodoamphetamin (IMP) is transiently taken up by the lungs
after intravenous injection and its concentration in arterial blood varies depending on the …

Superiority of HMPAO ictal SPECT to ECD ictal SPECT in localizing the epileptogenic zone

DS Lee, SK Lee, YK Kim, JS Lee, GJ Cheon… - …, 2002 - Wiley Online Library
Purpose: We examined diagnostic performances of Tc‐99m hexamethylpropylene amine
oxime (HMPAO) and Tc‐99m electron capture detection (ECD) ictal single‐photon emission …

Accuracy and reproducibility of co-registration techniques based on mutual information and normalized mutual information for MRI and SPECT brain images

T Yokoi, T Soma, H Shinohara, H Matsuda - Annals of nuclear medicine, 2004 - Springer
We implemented a 3D co-registration technique based on mutual information (MI) including
2D image matching as a coarse pre-registration. The 2D coarse pre-registration was …

Effects of aging on the cerebral distribution of technetium-99m hexamethylpropylene amine oxime in healthy humans

PD Mozley, AM Sadek, A Alavi, RC Gurt… - European journal of …, 1997 - Springer
Some brain functions decline at a linear rate throughout adulthood. Others remain relatively
stable until very late in the life cycle. This study characterized the effects of aging on the …

Lassen's Equation is a Good Approximation of Permeability-Surface Model: New α Values for 99mTc-HMPAO and 99mTc-ECD

M Kameyama - Journal of Cerebral Blood Flow & …, 2014 - journals.sagepub.com
Brain perfusion tracers like [99mTc] d, l-hexamethyl-propyeneamine oxime (99mTc-HMPAO)
and [99mTc] ethyl-cysteinate dimer (99mTc-ECD) underestimate regional cerebral blood …