Dopamine transporter (DAT) imaging is a sensitive method to detect presynaptic dopamine
neuronal dysfunction, which is a hallmark of neurodegenerative parkinsonism. DAT imaging …

Cognitive deficits are well documented in psychiatric disorders, particularly in schizophrenia
and depression. Cognitive activity roots in perceptions. However, research on sensorial …

OBJECTIVE: To evaluate whether visual assessment of [123I]-FP-CIT (DaTSCAN™,
Nycomed Amersham, plc) single photon emission computerized tomography (SPECT) …

OBJECTIVES: The main neuropathological feature in Parkinson's disease is a severe
degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of …

The variability in clinical features and the masking effects of drug therapy in Parkinson's
disease (PD) can affect clinical assessment of disease severity. The aim of this study was to …

Nv-fluoropropyl-2b-carbomethoxy-3b-(4-123I-iodophenyl) nortropane (123I-ioflupane) is a
molecular imaging agent used to demonstrate the location and concentration of dopamine …

Abstract [123 I] FP-CIT (N-ω-fluoropropyl-2β-carbomethoxy-3β-{4-iodophenyl} nortropane)
has been developed successfully as a radioligand for single-photon emission tomography …

Obesity results from an imbalance between energy intake and expenditure, and many
studies have aimed to determine why obese individuals continue to (over) consume food …

Functional imaging of the dopamine transporter (DAT) defines integrity of the dopaminergic
system and has its main clinical application in patients with mild, incomplete, or uncertain …

Background Preclinical and pathology evidence suggests an involvement of brain dopamine
(DA) circuitry in Alzheimer's disease (AD). We in vivo investigated if, when, and in which …