Anumber of techniques have been developed during the past four decades to evaluate
cerebral perfusion. The oldest used 133Xe, a lipophilic radioactive tracer that easily diffuses …

The availability of plastic microspheres labeled with different-emitting isotopes has allowed
the quantification of blood flow in different organs, including the heart (1). In the past 3 …

Molecular imaging is expected to change the face of drug discovery and development. The
ability to link imaging to biology for guiding therapy should improve the rate at which novel …

The increasing amount of clinically relevant information obtained by positron emission
tomography (PET), primarily with fluorine-18 labelled 2-deoxy-2-fluoro-d-glucose, has …

Abstract Purpose 2-Deoxy-2-[18 F] fluoro-d-glucose (FDG) is the most commonly used
positron emission tomography (PET) tracer for oncological and neurological imaging, but it …

Blood flow and hypoxia are interrelated aspects of physiology that affect cancer treatment
and response. Cu-PTSM and Cu-ATSM are related PET tracers for blood flow and hypoxia …

Positron emission tomography (PET) can characterize different aspects of tumor physiology
using various tracers. PET scans are usually performed using only one tracer since there is …

A series of four “mixed” bis (thiosemicarbazone) keto aldehyde derivatives containing
dissimilar thiosemicarbazone functions were synthesized and evaluated as ligands for …

Surrogate markers of clinical outcome are important in anticancer drug research, since
clinical criteria of response develop only slowly and may be confounded by other processes …

The two longer-lived copper radionuclides, 64Cu and 67Cu, have a long history of
application as biomedical tracers, notably in the use of 64Cu2+ and 67Cu2+ to probe …