Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides

S Liu - Advanced drug delivery reviews, 2008 - Elsevier
Receptor-based radiopharmaceuticals are of great current interest in molecular imaging and
radiotherapy of cancers, and provide a unique tool for target-specific delivery of …

Technetium and gallium derived radiopharmaceuticals: comparing and contrasting the chemistry of two important radiometals for the molecular imaging era

MD Bartholoma, AS Louie, JF Valliant… - Chemical …, 2010 - ACS Publications
The objective of medical imaging using molecular probes and perfusion radiotracers is to
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …

Radiolabeled peptides and antibodies in medicine

P Kręcisz, K Czarnecka, L Królicki… - Bioconjugate …, 2020 - ACS Publications
Radiolabeled peptides are a relatively new, very specific radiotracer group, which is still
expanding. This group is very diverse in terms of peptide size. It contains very small …

[BOOK][B] Bioinorganic chemistry: a short course

RM Roat-Malone - 2007 - books.google.com
An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short
Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry …

Peptide‐based radiopharmaceuticals: Future tools for diagnostic imaging of cancers and other diseases

SM Okarvi - Medicinal research reviews, 2004 - Wiley Online Library
An Erratum has been published for this article in Medicinal Research Reviews 2004; 24: 685–
686. Small synthetic receptor‐binding peptides are the agents of choice for diagnostic …

Metal complexes as diagnostic tools

DE Reichert, JS Lewis, CJ Anderson - Coordination Chemistry Reviews, 1999 - Elsevier
This review summarizes some of the developments of metal complexes and metal-complex-
bioconjugates for the diagnosis of disease states that have occurred over the past 10 years …

EP-2104R: a fibrin-specific gadolinium-Based MRI contrast agent for detection of thrombus

K Overoye-Chan, S Koerner, RJ Looby… - Journal of the …, 2008 - ACS Publications
Thrombus (blood clot) is implicated in a number of life threatening diseases, eg, heart attack,
stroke, pulmonary embolism. EP-2104R is an MRI contrast agent designed to detect …

[HTML][HTML] Radiolabeled cyclic RGD peptides as radiotracers for imaging tumors and thrombosis by SPECT

Y Zhou, S Chakraborty, S Liu - Theranostics, 2011 - ncbi.nlm.nih.gov
The integrin family is a group of transmembrane glycoprotein comprised of 19 α-and 8 β-
subunits that are expressed in 25 different α/β heterodimeric combinations on the cell …

99mTc Labeling of Highly Potent Small Peptides

S Liu, DS Edwards, JA Barrett - Bioconjugate chemistry, 1997 - ACS Publications
Peptides are compounds that contain amino acids (R-aminocarboxylic acids) linked by
amide (peptide) bonds. Designed by nature for stimulating, inhibiting, or regulating …

New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design

SR Banerjee, KP Maresca, L Francesconi… - Nuclear medicine and …, 2005 - Elsevier
Bifunctional chelates offer a general approach for the linking of radioactive metal cations to
macromolecules. In the specific case of 99mTc, a variety of technologies have been …