Restoration of Iodide Uptake in Dedifferentiated Thyroid Carcinoma: Relationship to Human Na+/I Symporter Gene Methylation Status

GM Venkataraman, M Yatin… - The Journal of Clinical …, 1999 - academic.oup.com
Disseminated dedifferentiated thyroid epithelial carcinoma, which cannot sufficiently
concentrate therapeutic radioiodide, is a terminal disease without any effective systemic …

Increased Expression of the Na+/I Symporter in Cultured Human Thyroid Cells Exposed to Thyrotropin and in Graves' Thyroid Tissue

T Saito, T Endo, A Kawaguchi, M Ikeda… - The Journal of …, 1997 - academic.oup.com
Abstract The Na+/I− symporter (NIS) is important in hormone synthesis in the thyroid gland.
NIS activity, as reflected by I− uptake, was increased by TSH (1 mU/mL) or forskolin (10μ …

Iodide uptake in human anaplastic thyroid carcinoma cells after transfer of the human thyroid peroxidase gene

U Haberkorn, A Altmann, S Jiang, I Morr… - European journal of …, 2001 - Springer
Human thyroperoxidase (hTPO) is critical for the accumulation of iodide in thyroid tissues.
Poorly differentiated and anaplastic thyroid tumours which lack thyroid-specific gene …

The management of metastatic differentiated thyroid carcinoma

SI Sherman - Reviews in Endocrine & Metabolic Disorders, 2000 - search.proquest.com
diagnosed thyroid carcinoma in the United States this year, 80% have papillary carcinoma
and 5s' 10% have follicular carcinoma [1]. These``differentiated carci-nomas''derive from the …

Electroporation: a novel approach to enhance the radioiodine uptake in a human thyroid cancer cell line

R Gopal, AA Narkar, KP Mishra, AM Samuel… - Applied radiation and …, 2003 - Elsevier
Radioiodine has been the best choice of treatment for differentiated thyroid cancer. Loss of
the ability to concentrate iodide makes thyroid cancer cells refractory to radioiodine therapy …

Binding of a human monoclonal antithyroglobulin antibody to cultured human thyroid cancer cells

T Misaki, MS Alam, H Sakahara, K Kasagi… - Annals of nuclear …, 1997 - Springer
To develop a new method of radioimmunodetection for thyroid cancer, we tested the binding
ability of a human antithyroglobulin monoclonal antibody, VB5, to primary culture of human …

New approaches in nuclear medicine for thyroid cancer

D Van Nostrand - Thyroid Cancer: A Comprehensive Guide to Clinical …, 2016 - Springer
When I wrote this chapter for the second edition of this textbook in 2006, I was not
necessarily writing about the future developments of nuclear medicine in thyroid cancer …

[PDF][PDF] Exponentially Decaying Electric Pulses for Improving Radioactive Iodine uptake in human thyroid cancer cells

AA Abd-Elghany - Health Sciences, 2016 - researchgate.net
Radioactive iodine (radioiodine) is an effective nuclear medicine treatment used to eradicate
thyroid cancer cells. The problem was the inability of thyroid cells to retain radioiodine which …

Iodine uptake restoration in thyroid cancer

KB Ain, G Venkataraman - US Patent 7,029,879, 2006 - Google Patents
A method of expressing a tumor specific therapeutic response element in a cancerous cell is
disclosed in which the response element was previously blocked from expression. The …

[BOOK][B] Das differenzierte Schilddrüsenkarzinom mit initialer Fernmetastasierung (Stadium M1): Diagnose, Therapie, Nachsorge und Prognose

T Petrich - 2000 - books.google.com
Anhand klinischer Studien wurden prognostische Faktoren erarbeitet, um den Einsatz der
relevanten diagnostischen Methoden zu optimieren und um im Sinne der …