Receptor-mediated and enzyme-dependent targeting of cytotoxic anticancer drugs

GM Dubowchik, MA Walker - Pharmacology & therapeutics, 1999 - Elsevier
This review is a survey of various approaches to targeting cytotoxic anticancer drugs to
tumors primarily through biomolecules expressed by cancer cells or associated vasculature …

Copper-67 as a therapeutic nuclide for radioimmunotherapy

I Novak-Hofer, AP Schubiger - European journal of nuclear medicine and …, 2002 - Springer
The application of the beta particle-emitting nuclide 67 Cu in radioimmunotherapy is
reviewed. The production of the nuclide is outlined, and different production modes are …

Pyridine- and Phosphonate-Containing Ligands for Stable Ln Complexation. Extremely Fast Water Exchange on the GdIII Chelates

E Balogh, M Mato-Iglesias, C Platas-Iglesias… - Inorganic …, 2006 - ACS Publications
Two novel ligands containing pyridine units and phosphonate pendant arms, with ethane-1,
2-diamine (L 2) or cyclohexane-1, 2-diamine (L 3) backbones, have been synthesized for Ln …

Synthesis, structures and luminescent properties of new heterobimetallic Zn-4f Schiff base complexes

WK Lo, WK Wong, J Guo, WY Wong, KF Li… - Inorganica chimica …, 2004 - Elsevier
A series of new 3d–4f heterobimetallic Schiff base complexes of the general formula [Zn (μ-
L2) Ln (NO3) 3 (H2O) n](Ln= La 1, Nd 2, Gd 3, Er 4 and Yb 5; n= 1 or 2; H2L2= N, N′-bis (3 …

Self-assembled dinuclear lanthanide helicates: substantial luminescence enhancement upon replacing terminal benzimidazole groups by carboxamide binding units

N Martin, JCG Bünzli, V McKee, C Piguet… - Inorganic …, 1998 - ACS Publications
The segmental ligands bis {1-alkyl-2-[6 '-(N, N-diethylcarbamoyl) pyridin-2 '-yl] benzimidazol-
5-yl} methane (alkyl= methyl (L5), ethyl (L6)) react with lanthanide perchlorates (Ln= La, Eu …

Physical parameters and biological stability of yttrium (III) diethylenetriaminepentaacetic acid derivative conjugates

TJ McMurry, CG Pippin, C Wu, KA Deal… - Journal of medicinal …, 1998 - ACS Publications
The solution equilibria, acid dissociation, and serum stability of a series of Y (III) complexes
of DTPA ligands functionalized with p-nitrobenzyl, methyl, and trans-cyclohexyl substituents …

Thermodynamics, conformation and active sites of the binding of Zn–Nd hetero-bimetallic Schiff base to bovine serum albumin

Q Xiao, S Huang, Y Liu, F Tian, J Zhu - Journal of fluorescence, 2009 - Springer
The interactions between N, N′-di (2-hydroxy-3-methyoxy-phenyl-1-methylene)-o-
phenyldiamine-mone Zn (II), Nd (III) nitrate (2LZnNd) and bovine serum albumin (BSA) was …

[BOOK][B] Applications and engineering of monoclonal antibodies

DJ King - 1998 - taylorfrancis.com
A valuable resource for researchers and workers in the fields of both pharmaceuticals and
biotechnology as well as undergraduates in biochemistry, applied biology, biomedical …

Structural and photophysical properties of heterobimetallic 4f-Zn iminophenolate cryptates

R Rodríguez-Cortiñas, F Avecilla… - Inorganic …, 2002 - ACS Publications
Lanthanide complexes with the Schiff base axial macrobicyclic ligand L1 react with Zn (II)
nitrate in the presence of CaH2 to yield Ln (III)− Zn (II) heterodinuclear cryptates with the …

High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170 …

CM Richman, SJ DeNardo, RT O'Donnell, A Yuan… - Clinical cancer …, 2005 - AACR
Purpose: Although radioimmunotherapy alone is effective in lymphoma, its application to
solid tumors will likely require a combined modality approach. In these phase I studies …