Therapeutic radiopharmaceuticals

WA Volkert, TJ Hoffman - Chemical reviews, 1999 - pubmed.ncbi.nlm.nih.gov

The pathophysiological consequences of somatostatin receptor internalization and resistance

LJ Hofland, SWJ Lamberts - Endocrine reviews, 2003 - academic.oup.com
Somatostatin receptors expressed on tumor cells form the rationale for somatostatin analog
treatment of patients with somatostatin receptor-positive neuroendocrine tumors …

In vivo tracking of 111In-oxine labeled mesenchymal stem cells following infusion in patients with advanced cirrhosis

A Gholamrezanezhad, S Mirpour, M Bagheri… - Nuclear medicine and …, 2011 - Elsevier
BACKGROUND: Several animal and few human studies suggest the beneficial role of bone
marrow mesenchymal stem cells (MSCs) in liver cirrhosis. However, little is known about the …

Somatostatin receptor-targeted radionuclide therapy of tumors: preclinical and clinical findings

M De Jong, R Valkema, F Jamar, LK Kvols… - Seminars in nuclear …, 2002 - Elsevier
In preclinical studies in rats we evaluated biodistribution and therapeutic effects of different
somatostatin analogs,[111In-DTPA] octreotide,[90Y-DOTA, Tyr3] octreotide and [177Lu …

Indium-111-pentetreotide prolongs survival in gastroenteropancreatic malignancies

LB Anthony, EA Woltering, GD Espenan… - Seminars in nuclear …, 2002 - Elsevier
Somatostatin and its analogues bind to somatostatin receptors (sst) 1 through 5 that are
overexpressed in neuroendocrine neoplasms such as gastroenteropancreatic (GEP) …

Auger radiation targeted into DNA: a therapy perspective

F Buchegger, F Perillo-Adamer, YM Dupertuis… - European journal of …, 2006 - Springer
Background Auger electron emitters that can be targeted into DNA of tumour cells represent
an attractive systemic radiation therapy goal. In the situation of DNA-associated decay, the …

[HTML][HTML] Radiolabelled somatostatin analogue (s) for peptide receptor scintigraphy and radionuclide therapy

EP Krenning, M De Jong, PPM Kooij, WAP Breeman… - Annals of …, 1999 - Elsevier
Background Peptide receptor scintigraphy with the radioactive somatostatin analogue,[111
In-DTPA 0] octreotide, is a sensitive and specific technique to show in vivo the presence and …

Kidney protection during peptide receptor radionuclide therapy with somatostatin analogues

EJ Rolleman, M Melis, R Valkema, OC Boerman… - European journal of …, 2010 - Springer
This review focuses on the present status of kidney protection during peptide receptor
radionuclide therapy (PRRT) using radiolabelled somatostatin analogues. This treatment …

Radiolabeled peptides in oncology: role in diagnosis and treatment

RE Weiner, ML Thakur - BioDrugs, 2005 - Springer
There has been an exponential growth in the development of radiolabeled peptides for
diagnostic and therapeutic applications in the last decade. The automated means of …

[PDF][PDF] 111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR

RM Reilly, R Kiarash, RG Cameron… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Overexpression of the epidermal growth factor (EGF) receptor (EGFR) at levels up to 100
times higher than that observed on normal epithelial cells has been observed in 30% — …