Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands
RB Innis, VJ Cunningham, J Delforge… - Journal of Cerebral …, 2007 - journals.sagepub.com
Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands - Robert B
Innis, Vincent J Cunningham, Jacques Delforge, Masahiro Fujita, Albert Gjedde, Roger N Gunn …
Innis, Vincent J Cunningham, Jacques Delforge, Masahiro Fujita, Albert Gjedde, Roger N Gunn …
The methodology of TSPO imaging with positron emission tomography
FE Turkheimer, G Rizzo, PS Bloomfield… - Biochemical Society …, 2015 - portlandpress.com
The 18-kDA translocator protein (TSPO) is consistently elevated in activated microglia of the
central nervous system (CNS) in response to a variety of insults as well as …
central nervous system (CNS) in response to a variety of insults as well as …
Dopamine D2 and D3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission …
F Yokoi, G Gründer, K Biziere, M Stephane… - …, 2002 - Elsevier
Aripiprazole (OPC 14597) is an antipsychotic drug that has high affinity for dopamine D2
and D3 receptors and the dopamine autoreceptor. It is being developed for treatment of …
and D3 receptors and the dopamine autoreceptor. It is being developed for treatment of …
Kinetic Modeling without Accounting for the Vascular Component Impairs the Quantification of [11C]PBR28 Brain PET Data
The positron emission tomography radioligand [11C] PBR28 targets translocator protein (18
kDa)(TSPO) and is a potential marker of neuroinflammation.[11C] PBR28 binding is …
kDa)(TSPO) and is a potential marker of neuroinflammation.[11C] PBR28 binding is …
Kinetic modelling of [11C]PBR28 for 18 kDa translocator protein PET data: A validation study of vascular modelling in the brain using XBD173 and tissue analysis
M Veronese, T Reis Marques… - Journal of Cerebral …, 2018 - journals.sagepub.com
The 18 kDa translocator protein (TSPO) is a marker of microglia activation in the central
nervous system and represents the main target of radiotracers for the in vivo quantification of …
nervous system and represents the main target of radiotracers for the in vivo quantification of …
Generalization of endothelial modelling of TSPO PET imaging: considerations on tracer affinities
The 18 kDa translocator protein (TSPO) is a marker of microglia activation and the main
target of positron emission tomography (PET) ligands for neuroinflammation. Previous works …
target of positron emission tomography (PET) ligands for neuroinflammation. Previous works …
In vivo extrastriatal and striatal D2 dopamine receptor blockade by amisulpride in schizophrenia
Amisulpride, a substituted benzamide with high affinity for dopamine D 2 and D 3 receptors
only, has been reported to have therapeutic effects on both negative and positive …
only, has been reported to have therapeutic effects on both negative and positive …
Potential Therapeutic Applications of Adenosine A2A Receptor Ligands and Opportunities for A2A Receptor Imaging
A van Waarde, RAJO Dierckx, X Zhou… - Medicinal Research …, 2018 - Wiley Online Library
Abstract Adenosine A2A receptors (A2ARs) are highly expressed in the human striatum, and
at lower densities in the cerebral cortex, the hippocampus, and cells of the immune system …
at lower densities in the cerebral cortex, the hippocampus, and cells of the immune system …
Differentiation of extrastriatal dopamine D2 receptor density and affinity in the human brain using PET
Dopaminergic neurotransmission in extrastriatal regions may play a crucial role in the
pathophysiology and treatment of neuropsychiatric disorders. The high-affinity radioligands …
pathophysiology and treatment of neuropsychiatric disorders. The high-affinity radioligands …
Acute increases in synaptic GABA detectable in the living human brain: a [11C] Ro15-4513 PET study
The inhibitory γ-aminobutyric acid (GABA) neurotransmitter system is associated with the
regulation of normal cognitive functions and dysregulation has been reported in a number of …
regulation of normal cognitive functions and dysregulation has been reported in a number of …