Inflammation and Alzheimer's disease

H Akiyama, S Barger, S Barnum, B Bradt, J Bauer… - Neurobiology of …, 2000 - Elsevier
Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

[PDF][PDF] The role of apolipoprotein E in Alzheimer's disease

J Kim, JM Basak, DM Holtzman - Neuron, 2009 - cell.com
The ɛ4 allele of apolipoprotein E (APOE) is the major genetic risk factor for Alzheimer's
disease (AD). Although there have been numerous studies attempting to elucidate the …

[HTML][HTML] EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3

E Guedj, A Varrone, R Boellaard, NL Albert… - European journal of …, 2022 - Springer
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …

Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease

S Minoshima, B Giordani, S Berent… - Annals of Neurology …, 1997 - Wiley Online Library
This study investigated cerebral glucose metabolism in very early Alzheimer's disease,
before a clinical diagnosis of probable Alzheimer's disease is possible, using [18F] …

[HTML][HTML] Imaging techniques in Alzheimer's disease: a review of applications in early diagnosis and longitudinal monitoring

WM van Oostveen, ECM de Lange - International journal of molecular …, 2021 - mdpi.com
Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

[HTML][HTML] Preclinical evidence of Alzheimer's disease in persons homozygous for the ε4 allele for apolipoprotein E

EM Reiman, RJ Caselli, LS Yun, K Chen… - … England Journal of …, 1996 - Mass Medical Soc
Background Variants of the apolipoprotein E allele appear to account for most cases of late-
onset Alzheimer's disease, and persons with two copies of the ε4 allele appear to have an …

[HTML][HTML] Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease

X Wang, W Huang, L Su, Y Xing, F Jessen… - Molecular …, 2020 - Springer
Subjective cognitive decline (SCD) is regarded as the first clinical manifestation in the
Alzheimer's disease (AD) continuum. Investigating populations with SCD is important for …

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

EM Reiman, K Chen, GE Alexander… - Proceedings of the …, 2004 - National Acad Sciences
Fluorodeoxyglucose positron emission tomography (PET) studies have found that patients
with Alzheimer's dementia (AD) have abnormally low rates of cerebral glucose metabolism …

Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease: FDG-PET studies in MCI and AD

L Mosconi - European journal of nuclear medicine and molecular …, 2005 - Springer
The demographics of aging suggest a great need for the early diagnosis of dementia and
the development of preventive strategies. Neuropathology and structural MRI studies have …

Neuropsychologic profiles and cerebral glucose metabolism in neurocognitive long COVID syndrome

A Dressing, T Bormann, G Blazhenets… - Journal of Nuclear …, 2022 - Soc Nuclear Med
During the coronavirus disease 2019 (COVID-19) pandemic, Long COVID syndrome, which
impairs patients through cognitive deficits, fatigue, and exhaustion, has become increasingly …