Zinc (Zn) and copper (Cu) are essential for optimal innate immune function, and nutritional
deficiency in either metal leads to increased susceptibility to bacterial infection. Recently, the …

The chemistry, radiochemistry, radiobiology, and radiopharmacology of
radiopharmaceuticals containing copper radionuclides are reviewed. Copper radionuclides …

89Zr (half-life, 78.41 h) is a positron-emitting radionuclide that displays excellent potential for
use in the design and synthesis of radioimmunoconjugates for immunoPET. In the current …

Copper-64 (T 1 2= 12.7 h) is an intermediate-lived positron-emitting radionuclide that is a
useful radiotracer for positron emission tomography (PET) as well as a promising …

The development of novel multimodality imaging agents and techniques represents the
current frontier of research in the field of medical imaging science. However, the …

High radiolabeling efficiency, preferably to high specific activity, and good stability of the
radioimmunoconjugate are essential features for a successful immunoconjugate for imaging …

Molecular imaging is an important scientific discipline that plays a major role in clinical
medicine and pharmaceutical development. While several imaging modalities including X …

Positron emission tomography (PET) has become a vital imaging modality in the diagnosis
and treatment of disease, most notably cancer. A wide array of small molecule PET …

Only a handful of radiolabeled antibodies (Abs) have gained US Food and Drug
Administration (FDA) approval for use in clinical oncology, including four immunodiagnostic …

Systemic administration of hypoxia-selective 64Cu-diacetyl-bis (N 4-
methylthiosemicarbazone)(64Cu-ATSM) has increased significantly the survival time of …