The selective destruction of malignant cells using an immunoconjugate is attractive because
of the apparent simplicity of the concept. A carrier molecule possessing desired affinity for …

Purpose Radionuclide therapy (RNT) is a rapidly growing area of clinical nuclear medicine,
wherein radionuclides are employed to deliver cytotoxic dose of radiation to the diseased …

Over the last 5 years, studies applying the chimeric anti-CD20 MAb have renewed
enthusiasm and triggered world-wide application of anti-CD20 MAb-based therapies in B …

REFERENCES Page 1 REFERENCES l. Hall P. Holm LE, Lundell G. et al. Cancer risks in
thyroid cancer patients. Br./ Cancer 1991:64; || 59 - || 63, 2. IARC Study Group on Cancer Risk …

Among the radionuclides considered for radioimmunotherapy, α-emitters such as the
bismuth isotopes, 212Bi and 213Bi, are of particular interest. The macrocyclic ligand, DOTA …

For the development of calix [4] arene-based radiotherapeutic agents, the conjugation to
biomolecules and immunogenicity in mice of potential 225Ac3+-chelating calix [4] arenes …

The use of radionuclides for medical and for a multitude of other basic research applications
has continued to grow at a very rapid pace. Procedures, based on their use as radiotracers …

Metallic radioimmunoconjugates have promise for radioimmunoimaging and therapy.
Macrocyclic chelating agents allow formation of stable metallic radioimmunoconjugates but …

Monoclonal antibodies (MAbs) labeled with radiometallonuclides via metal chelators are
being investigated in the laboratory for use in clinical trials. The biodistribution of 111In-and …

Purpose Cotinine has optimal characteristics as a hapten for pre-targeted
radioimmunotherapy (PRIT). This study was performed to evaluate the applicability of …