Acromegaly was defined as a syndrome by Pierre Marie in 1885, but in the form of either
acromegaly or acrogigantism has probably been a disorder of antiquity [1, 2]. It is one of the …

Impaired cardiovascular function has recently been demonstrated to potentially reduce life
expectancy both in GH deficiency and excess. Experimental and clinical studies have …

Secondary hypertension affects a small but significant number of the hypertensive
population and, unlike primary hypertension, is a potentially curable condition. The …

To evaluate the relative contributions of past or present GH hypersecretion and of
hypertension to the cardiac abnormalities present in acromegaly, we have studied the serum …

Acromegalic patients are considered to be exposed to a doubled mortality rate, mostly for
cardiovascular diseases. This open prospective study was designed to evaluate whether the …

The aim of the study was to investigate the effects of 1-yr treatment with octreotide (OCT) on
left ventricular diastolic and systolic function, assessed at rest and during physical exercise …

OBJECTIVE The interpretation of echocardiographic abnormalities in acromegalic patients
is complicated by non‐specific age‐related diseases, many of which are commoner in …

The aim of this study was to evaluate the impact of age and disease duration on cardiac
performance in acromegaly. To address these issues, the left ventricular function at rest and …

Cardiovascular disease is claimed to be one of the most severe complications of
acromegaly, contributing significantly to mortality in this disease. In fact, an excess of growth …

Cardiac involvement, mostly characterized by left ventricular hypertrophy associated with
various degrees of cardiac dysfunction, greatly contributes to the increased mortality and …