Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting

A Meyer, J Auernheimer, A Modlinger… - Current …, 2006 - ingentaconnect.com
Integrins constitute an important class of cell adhesion receptors responsible not only for cell-
matrix adhesion but also for signaling bidirectionally across the membrane. Integrins are …

[HTML][HTML] The role of molecular imaging in diagnosis of deep vein thrombosis

S Houshmand, A Salavati, S Hess… - American journal of …, 2014 - ncbi.nlm.nih.gov
Venous thromboembolism (VTE) mostly presenting as deep venous thrombosis (DVT) and
pulmonary embolism (PE) affects up to 600,000 individuals in United States each year …

Detection and characterization of thrombosis in humans using fibrin-targeted positron emission tomography and magnetic resonance

D Izquierdo-Garcia, P Désogère, AL Philip… - Cardiovascular …, 2022 - jacc.org
Objectives The authors present a novel technique to detect and characterize LAA thrombus
in humans using combined positron emission tomography (PET)/cardiac magnetic …

Thrombus imaging using technetium-99m-labeled high-potency GPIIb/IIIa receptor antagonists. Chemistry and initial biological studies

DA Pearson, J Lister-James, WJ McBride… - Journal of medicinal …, 1996 - ACS Publications
Platelet-specific compounds which are radiolabeled with γ-emitting radionuclides may be
particularly useful for the noninvasive in vivo detection of thrombi. The synthesis of peptides …

Receptor imaging: competitive or complementary to antibody imaging?

SJ Goldsmith - Seminars in nuclear medicine, 1997 - Elsevier
Both radiolabeled ligands to specific receptors on cell surfaces and radiolabeled antibodies
to specific cell surface epitopes provide new opportunities to scintigraphically identify …

[BOOK][B] Handbook of targeted delivery of imaging agents

VP Torchilin - 1995 - books.google.com
This is the first time detailed and updated information on the targeted delivery of imaging
agents has been collected into a single handbook. This comprehensive volume presents the …

Preparation and Characterization of [99TcO] Apcitide:  A Technetium Labeled Peptide

LC Francesconi, Y Zheng, J Bartis… - Inorganic …, 2004 - ACS Publications
[99mTcO] apcitide (99mTcO (P246)), the technetium complex of the 13 amino acid, apcitide,
cyclo-(d-Tyr-Apc-Gly-Asp-Cys)-Gly-Gly-Cys (Acm)-Gly-Cys (Acm)-Gly-Gly-Cys-NH2, where …

Method for treating occlusive peripheral vascular disease and coronary disease

HV Barron, E Botvinick - US Patent 6,440,947, 2002 - Google Patents
Compositions and methods for treatment of occlusive peripheral vascular disease and
coronary disease are dis closed. The compositions and methods alloW treatment of …

[PDF][PDF] Pre-clinical evaluation of technetium-99m platelet receptor-binding peptide

J Lister-James, S Vallabhajosula… - Journal of Nuclear …, 1997 - Soc Nuclear Med
P748 in deep vein and pulmonary thrombi was assessed in a canine thrombosis model and
the biodistribution of 99nrTc-P748was de termined in rats. Results: P748 peptide inhibited …

Imaging of deep venous thrombosis in patients using a radiolabelled anti-D-dimer Fab′ fragment (99mTc-DI-DD3B6/22-80B3): results of a phase I trial

D Macfarlane, A Socrates, P Eisenberg… - European journal of …, 2009 - Springer
Abstract Purpose 99m Tc-DI-DD3B6/22-80B3 (ThromboView®, hereafter abbreviated to
99m Tc-DI-80B3 Fab′) is a radiolabelled humanised monoclonal Fab′ fragment with …