[HTML][HTML] Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future …
A Dimitrakopoulou-Strauss, L Pan… - European journal of …, 2021 - Springer
Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …
Although it is generally accepted that the information provided by dPET is superior to that of …
[HTML][HTML] Long axial field of view (LAFOV) PET-CT: implementation in static and dynamic oncological studies
A Dimitrakopoulou-Strauss, L Pan… - European Journal of …, 2023 - Springer
Long axial field of view (LAFOV) PET-CT scanners have been recently developed and are
already in clinical use in few centers worldwide. Although still limited, the hitherto acquired …
already in clinical use in few centers worldwide. Although still limited, the hitherto acquired …
Quantifying regional hypoxia in human tumors with positron emission tomography of [18F] fluoromisonidazole: a pretherapy study of 37 patients
JS Rasey, W Koh, ML Evans, LM Peterson… - International Journal of …, 1996 - Elsevier
Purpose: To assess pretreatment hypoxia in a variety of tumors using positron emission
tomography (PET) after injection of the hypoxia-binding radiopharmaceutical [“'F] …
tomography (PET) after injection of the hypoxia-binding radiopharmaceutical [“'F] …
Imaging P‐glycoprotein transport activity at the human blood‐brain barrier with positron emission tomography
Background Numerous knockout mouse studies have revealed that P‐glycoprotein (P‐gp)
significantly limits drug distribution across the mouse blood‐brain barrier (BBB). To …
significantly limits drug distribution across the mouse blood‐brain barrier (BBB). To …
In Vivo Validation of 3′deoxy-3′-[18F]fluorothymidine ([18F]FLT) as a Proliferation Imaging Tracer in Humans: Correlation of [18F]FLT Uptake by …
H Vesselle, J Grierson, M Muzi, JM Pugsley… - Clinical cancer …, 2002 - AACR
Purpose: Tumor proliferation has prognostic value in resectedearly stage non-small cell lung
cancer (NSCLC) and can, therefore, predict which NSCLCs are at high risk for recurrence …
cancer (NSCLC) and can, therefore, predict which NSCLCs are at high risk for recurrence …
18F-FDG PET of gliomas at delayed intervals: improved distinction between tumor and normal gray matter
AM Spence, M Muzi, DA Mankoff… - Journal of Nuclear …, 2004 - Soc Nuclear Med
We hypothesized that delineation of gliomas from gray matter with 18F-FDG PET could be
improved by extending the interval between 18F-FDG administration and PET data …
improved by extending the interval between 18F-FDG administration and PET data …
Characteristics of a new fully programmable blood sampling device for monitoring blood radioactivity during PET
R Boellaard, A van Lingen, SCM van Balen… - European journal of …, 2001 - Springer
The first performance tests of a new fully programmable blood sampling device for
monitoring blood radioactivity during positron emission tomography (PET) are described …
monitoring blood radioactivity during positron emission tomography (PET) are described …
Imaging of cyclosporine inhibition of P-glycoprotein activity using 11C-verapamil in the brain: studies of healthy humans
The multiple-drug resistance (MDR) transporter P-glycoprotein (P-gp) is highly expressed at
the human blood–brain barrier (BBB). P-gp actively effluxes a wide variety of drugs from the …
the human blood–brain barrier (BBB). P-gp actively effluxes a wide variety of drugs from the …
Kinetic analysis of 3′-deoxy-3′-18F-fluorothymidine in patients with gliomas
M Muzi, AM Spence, F O'Sullivan… - Journal of Nuclear …, 2006 - Soc Nuclear Med
3′-Deoxy-3′-fluorothymidine (FLT), a thymidine analog, is under investigation for
monitoring cellular proliferation in gliomas, a potential measure of disease progression and …
monitoring cellular proliferation in gliomas, a potential measure of disease progression and …
The FDG lumped constant in normal human brain
MM Graham, M Muzi, AM Spence… - Journal of Nuclear …, 2002 - Soc Nuclear Med
The lumped constant (LC) is a correction factor used to infer glucose metabolic rate (MRglc)
from FDG metabolic rate (MRFDG). Methods: LC was determined in normal brain in 10 …
from FDG metabolic rate (MRFDG). Methods: LC was determined in normal brain in 10 …