Evaluation in vitro and in rats of161Tb-DTPA-octreotide, a somatostatin analogue with potential for intraoperative scanning and radiotherapy

M de Jong, WAP Breeman, BF Bernard… - European journal of …, 1995 - Springer
The characteristics of terbium-161 diethylene triamine penta-acetic acid (DTPA) labelled
octreotide with respect to specific binding to somatostatin (octreotide) receptors on rat brain …

PET-pharmacokinetics of 18F-octreotide: A comparison with 67Ga-DFO and 86Y-DTPA-octreotide

HJ Wester, J Brockmann, F Rösch, W Wutz… - Nuclear medicine and …, 1997 - Elsevier
The quantitative uptake kinetics of (2-[18F] fluoropropionyl-(D) phe1)-Octreotide (I), a
somatostatin (SRIF) receptor-specific tracer, was measured by PET. Conventional organ …

Choice of radionuclides and radiolabelling techniques

V Tolmachev - Targeted Radionuclide Tumor Therapy: Biological …, 2008 - Springer
Considerations on the choice of type of radionuclide suitable for tumour therapy are given.
The physical properties of the radionuclides in relation to the therapy conditions are …

Receptor-mediated tumor targeting with radiopeptides. Part 1. General concepts and methods: applications to somatostatin receptor-expressing tumors

AN Eberle, G Mild, S Froidevaux - Journal of Receptors and Signal …, 2004 - Taylor & Francis
Radiolabeled peptides have become important tools in nuclear oncology, both as
diagnostics and more recently also as therapeutics. They represent a distinct sector of the …

Biodistribution of [111In-DTPA-D-Phe1]-octreotide in dogs: uptake in the stomach and intestines but not in the spleen points towards interspecies differences

J Robben, JC Reubi, Y Pollak, G Voorhout - Nuclear medicine and biology, 2003 - Elsevier
The purpose of the present study was to establish the tissue distribution in abdominal
organs and the excretion of radioactivity after intravenous administration of [111In-DTPA-d …

Strategies for radioligand development: Peptides for tumor targeting

G Stöcklin, HJ Wester - … emission tomography: A critical assessment of …, 1998 - Springer
Tumors express numerous specific receptors for peptide ligands (Eckelman 1994, Reubi
1995). Thus, the development and application of peptides and proteins, including …

Labeling of the peptide DOTA-tyr3-octreotate with radioiodine and biodistribution and AR42J neuroendocrine tumor affinity study in mice

LT Nagamati - inis.iaea.org
Neuroendocrine tumors are rare and affect mainly the gastrointestinal tract but other systems
are also affected like the skin, lungs and the nervous system. They are rich in type 2 …

Breast Imaging with Radiolabeled Peptides

EP Krenning, M de Jong, R Valkema… - … Imaging of the Breast, 2021 - books.google.com
Since somatostatin and its analogs (and their receptors) are the most frequently discussed
and used of all peptides in relation to breast cancer scintigraphy, their application is the …

Labeling of the peptide DOTA-tyr {sup 3}-octreotate with radioiodine and biodistribution and AR42J neuroendocrine tumor affinity study in mice; Marcacao do peptideo …

LT Nagamati - 2006 - osti.gov
Neuroendocrine tumors are rare and affect mainly the gastrointestinal tract but other systems
are also affected like the skin, lungs and the nervous system. They are rich in type 2 …

[PDF][PDF] In vivo Glucagon-like Peptide 1 Rezeptorbildgebung mittels radiometallmarkiertem Exendin-4.

KJ Klose - Regul Pept - core.ac.uk
Erstmals wurde die Existenz von GLP-1 von Moore et al. im Jahre 1906 beschrieben. Seine
Arbeitsgruppe vermutete eine Substanz die eine ähnliche Wirkung auf das endokrine …