A promising new treatment for glioma involves Auger electron emitters such as 125I or 123I
conjugated to deoxyuridine (IUdR). However, the presence in tumour deposits of non …

We recently reported the conversion of the water-soluble antiviral drug iododeoxyuridine
(IDU) into the lipophilic prodrug dioleoyl-iododeoxyuridine (IDU-Ol2). The prodrug was …

Pretarget radioimmunotherapy (RIT) is a multistep strategy for cancer therapy designed to
reduce nontarget organ exposure by uncoupling the tumor targeting moiety from the …

Background. Although treatment with radiolabeled monoclonal antibodies (MoAb) against
tumor‐associated antigens offers the potential for targeted therapy, the efficacy of this …

Purpose: To extend our findings in previous radiation and biochemical studies with five
rodent tumors, in whichwe used one and occasionally two or three irradiations. The extent of …

Targeted radionuclide therapy of cancer | SpringerLink Skip to main content Advertisement
SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart Book …

Colon cancer is the third most common cancer diagnosed in men and women in the USA,
with∼ 103,000 new cases in 2010, but it ranks second among all cancer-related deaths in …

It has been 45 years since the first indication that radioimmunotherapy (RIT) might be a
feasible approach to therapy of cancer. Since then, especially during the past decade, many …

Monoclonal antibodies (MoAbs) have had a major impact on many aspects of cancer
research and diagnosis [1, 2]. Clinical trials for therapy including the use of murine MoAbs …

A modified method for the synthesis of radioiodinated 5‐iodo‐2′‐deoxyuridine based on
electrophillic iodination using concentrated HNO3 as an oxidising agent is described. It is …