Results: In all patients with antigen-positive tumors (n= 13), the primary tumors and all
known metastases were clearly visualized. Overall uptake, expressed as the percentage of …

Methods and compositions for medical imaging, evaluating intracellular processes and
components, radiotherapy of intracellular targets, and drug delivery by the use of novel cell …

The Indium-labelled somatostatin analogue pentetreotide has been successfully developed
for imaging of somatostatin receptor positive tumours. However there is significant renal …

+ 39%. Conclusion: Even though quantitative SPECT is the most rigorous method for activity
quantification in conditions of low organ-to-background activity concentration ratio, planar …

Amatuximab is a chimeric high-affinity monoclonal IgG1/k antibody targeting mesothelin that
is being developed for treatment of mesothelin-expressing cancers. Considering the …

The renal uptake of radiolabeled antibody fragments presents a problem in targeted imaging
and therapy. We hypothesized that the renal radioactivity levels of radiolabeled antibody …

Interleukin 8 (IL-8) is a chemotactic cytokine that binds with a high affinity to receptors
expressed on neutrophils. Previous studies with various animal models showed that 99mTc …

The bispecific monoclonal antibody (biMAb) OC/TR combines the anti‐ovarian‐cancer
reactivity of the MOv18 monoclonal antibody (MAb) with the reactivity of an anti‐CD3 MAb …

Purpose: There is increasing evidence that the chimeric monoclonal antibody G250 (cG250)
can be internalized by G250 antigen-expressing renal cell carcinoma (RCC) cells. Thus …

Objectives Internal organ dosimetry is an important procedure to demonstrate the reliable
application of 177 Lu-trastuzumab radioimmunotherapy for human epidermal growth factor …