[HTML][HTML] PET/CT in oncology: current status and perspectives

J Czernin, M Allen-Auerbach, D Nathanson… - Current radiology …, 2013 - Springer
The discovery of the Warburg effect in the early twentieth century followed by the
development of the fluorinated glucose analogue 18 F-fluorodeoxyglucose (18 F-FDG) and …

Molecular imaging of prostate cancer: PET radiotracers

H Jadvar - American Journal of Roentgenology, 2012 - Am Roentgen Ray Soc
OBJECTIVE. Recent advances in the fundamental understanding of the complex biology of
prostate cancer have provided an increasing number of potential targets for imaging and …

Tumor localization of 16β-18F-fluoro-5α-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer

SM Larson, M Morris, I Gunther, B Beattie… - Journal of Nuclear …, 2004 - Soc Nuclear Med
This trial was an initial assessment of the feasibility, in vivo targeting, and biokinetics of 16β-
18F-fluoro-5α-dihydrotestosterone (18F-FDHT) PET in patients with metastatic prostate …

Sigma-2 receptors as a biomarker of proliferation in solid tumours

KT Wheeler, LM Wang, CA Wallen, SR Childers… - British journal of …, 2000 - nature.com
Over the past several years, our group has provided considerable evidence that the
expression of sigma-2 (σ 2) receptors may serve as a biomarker of tumour cell proliferation …

Positron tomographic assessment of androgen receptors in prostatic carcinoma

F Dehdashti, J Picus, JM Michalski, CS Dence… - European journal of …, 2005 - Springer
Purpose The purpose of this study was to evaluate the feasibility of androgen receptor (AR)
imaging with 16β-[18 F] fluoro-5α-dihydrotestosterone (FDHT) by positron emission …

Fluorinated tracers for imaging cancer with positron emission tomography

O Couturier, A Luxen, JF Chatal, JP Vuillez… - European journal of …, 2004 - Springer
[18 F] fluoro-2-deoxy-d-glucose (FDG) is currently the only fluorinated tracer used in routine
clinical positron emission tomography (PET). Fluorine-18 is considered the ideal …

Androgen and estrogen receptor imaging in metastatic breast cancer patients as a surrogate for tissue biopsies

CM Venema, LH Mammatas, CP Schröder… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In addition to the well-known estrogen receptor (ER) and human epidermal growth factor
receptor 2, the androgen receptor (AR) is also a potential drug target in breast cancer …

The next generation of positron emission tomography radiopharmaceuticals in oncology

SL Rice, CA Roney, P Daumar, JS Lewis - Seminars in nuclear medicine, 2011 - Elsevier
Although 18 F-fluorodeoxyglucose (18 F-FDG) is still the most widely used positron emission
tomography (PET) radiotracer, there are a few well-known limitations to its use. The last …

Sex steroid hormones and brain function: PET imaging as a tool for research

R Moraga‐Amaro, A Van Waarde… - Journal of …, 2018 - Wiley Online Library
Sex steroid hormones are major regulators of sexual characteristic among species. These
hormones, however, are also produced in the brain. Steroidal hormone‐mediated signalling …

Organomediated Enantioselective 18F Fluorination for PET Applications

F Buckingham, AK Kirjavainen, S Forsback… - Angewandte …, 2015 - Wiley Online Library
The first organomediated asymmetric 18F fluorination has been accomplished using a chiral
imidazolidinone and [18F] N‐fluorobenzenesulfonimide. The method provides access to …