Radiopharmaceuticals for brain imaging

GB Saha, WJ MacIntyre, RT Go - Seminars in nuclear medicine, 1994 - Elsevier
Brain imaging is performed using radiopharmaceuticals by single photon emission
computed tomography (SPECT) and positron emission tomography (PET). SPECT and PET …

[HTML][HTML] Benzamide derivative radiotracers targeting melanin for melanoma imaging and therapy: Preclinical/clinical development and combination with other …

J Rouanet, M Quintana, P Auzeloux, F Cachin… - Pharmacology & …, 2021 - Elsevier
Cutaneous melanoma arises from proliferating melanocytes, cells specialized in the
production of melanin. This property means melanin can be considered as a target for …

[PDF][PDF] Dopamine D2 receptor imaging with iodine-123-iodobenzamide SPECT in idiopathic rotational torticollis

J Hierholzer, M Cordes, L Schelosky… - Journal of Nuclear …, 1994 - Soc Nuclear Med
Dopamine D2 Receptor Imaging with Iodine-123-Iodobenzamide SPECT in Idiopathic Rotational
Torticollis Page 1 may show rotationaltorticollis, laterocollis, retrocollis or combinations thereof …

Comparison of transcranial sonography, magnetic resonance imaging, and single photon emission computed tomography findings in idiopathic spasmodic torticollis

G Becker, M Naumann, M Scheubeck… - … : official journal of the …, 1997 - Wiley Online Library
Various lines of evidence suggest that the basal ganglia and thalamus are involved in the
pathogenesis of idiopathic dystonia, but unfortunately neuroradiological and pathological …

Dual SPECT of dopamine system using [99mTc] TRODAT-1 and [123I] IBZM in normal and 6-OHDA-lesioned formosan rock monkeys

KH Ma, WS Huang, CH Chen, SZ Lin, SP Wey… - Nuclear Medicine and …, 2002 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by a
severe loss of the dopaminergic neurons in the substantia nigra pars compacta. In this study …

[HTML][HTML] Neuroprotective effects of Jitai tablet, a traditional Chinese medicine, on the MPTP-induced acute model of Parkinson's disease: involvement of the dopamine …

J Liu, J Gao, S Tu, S Xu, Y Liu, W Shang… - Evidence-Based …, 2014 - hindawi.com
Jitai tablet (JTT) is a traditional Chinese medicine used to treat neuropsychiatric disorders.
We previously demonstrated that JTT treatment led to increased level of dopamine …

Single-photon emission tomography

K Goffin, K Van Laere - Handbook of Clinical Neurology, 2016 - Elsevier
Single-photon emission computed tomography (SPECT) is a functional nuclear imaging
technique that allows visualization and quantification of different in vivo physiologic and …

Radioiodination chemistry and radioiodinated compounds

M Eisenhut, W Mier - Handbook of nuclear chemistry, 2011 - ui.adsabs.harvard.edu
An overview of the chemistry of radioiodination is presented. The focus is directed on the
labeling of iodine-containing radiopharmaceuticals, with emphasis on practical aspects of …

[99mTc] TRODAT-1/[123I] IBZM SPECT studies of the dopaminergic system in Tourette syndrome

WJ Hwang, WJ Yao, YK Fu, AS Yang - Psychiatry Research: Neuroimaging, 2008 - Elsevier
The good clinical effectiveness of dopamine depleter and receptor antagonists on tics
suggests dopaminergic hyperactivity in Tourette syndrome (TS). In this case-control study of …

Downregulation of striatal dopamine D2 receptors in advanced Parkinson's disease contributes to the development of motor fluctuation

WJ Hwang, WJ Yao, SP Wey, LH Shen, G Ting - European neurology, 2002 - karger.com
The purpose of this study was to evaluate the contribution of the postsynaptic mechanism to
the development of motor fluctuation in advanced Parkinson's disease (PD). We used 123I …