Identifying biomarkers that can be used as diagnostics or predictors of treatment response
(theranostics) in people with schizophrenia (Sz) will be an important step towards being able …

J. Neurochem.(2011) 117, 333–345. Abstract We have obtained, for the first time, a
quantitative protein expression profile of membrane transporters and receptors in human …

The aim of the study was to develop a simple 18F-labeledamino acid as a PET tracer for
cerebral and peripheral tumors. O (2-[18F] fluoroethyl)-L-tyrosine (i_-[18F] FET) was …

In vivo functional brain imaging, including global blood flow, regional cerebral blood flow
(rCBF), measured with positron emission tomography (PET) and single photon emission …

The blood-brain barrier (BBB) permeabilities of 11 compounds were measured both in vitro
with a newly developed coculture-based model of human BBB and in vivo with positron …

Positron emission tomography (PET) provides unbiased in vivo measurement of local tracer
activity at very high sensitivity. This is a unique property unmatched by other imaging …

Background There is evidence that patients with schizophrenia exhibit abnormalities, not
only in the brain but also in peripheral organs. An abnormal cell membrane composition has …

Blood‐brain barrier permeability to phenylalanine and leucine in four patients with
phenylketonuria and in four volunteers was measured five times by the double‐indicator …

O-(2-18F-fluoroethyl)-l-tyrosine (18F-FET) is a radiolabeled artificial amino acid used in PET
for tumor delineation and grading. The present study compares different kinetic models to …

Human fibroblast cells are an advantageous model to study the transport of amino acids
across cell membranes, since one can control the environmental factors. A major problem in …