Fluorinated amino acids for tumour imaging with positron emission tomography

P Laverman, OC Boerman, FH Corstens… - European journal of …, 2002 - Springer
The currently preferred radiopharmaceutical for positron emission tomography (PET) in
oncology is 2-[18 F] fluoro-deoxyglucose (FDG). Increased accumulation of this …

Fluorinated tracers for imaging cancer with positron emission tomography

O Couturier, A Luxen, JF Chatal, JP Vuillez… - European journal of …, 2004 - Springer
[18 F] fluoro-2-deoxy-d-glucose (FDG) is currently the only fluorinated tracer used in routine
clinical positron emission tomography (PET). Fluorine-18 is considered the ideal …

Quantitative PET studies in pretreated melanoma patients: a comparison of 6-[18F] fluoro-L-dopa with 18F-FDG and 15O-water using compartment and …

A Dimitrakopoulou-Strauss, LG Strauss… - Journal of Nuclear …, 2001 - Soc Nuclear Med
The purpose of the study was to evaluate the 6-[18F] fluoro-l-dopa (FDOPA) kinetics with
PET in patients with treated melanoma metastases and to compare it with the standard …

4-Borono-2-[18F] fluoro-D, L-phenylalanine as a target compound for boron neutron capture therapy: tumor imaging potential with positron emission tomography

K Ishiwata, T Ido, M Kawamura, K Kubota… - International journal of …, 1991 - Elsevier
We studied the tumor uptake and metabolism of 4-borono-2-[18 F] fluoro-d, l-phenylalanine
([18 F] FBPA), an 18 F-labeled target compound for boron neutron capture therapy. In mice …

5-(2-18F-fluoroethoxy)-L-tryptophan as a substrate of system L transport for tumor imaging by PET

SD Krämer, L Mu, A Müller, C Keller… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Large neutral l-amino acids are substrates of system L amino acid transporters. The level of
one of these, LAT1, is increased in many tumors. Aromatic l-amino acids may also be …

Molecular imaging of tumor metabolism and apoptosis

U Haberkorn, A Markert, W Mier, V Askoxylakis… - Oncogene, 2011 - nature.com
Increased metabolism in a number of cellular pathways is a common feature of malignant
tumors. This metabolic hallmark of neoplastic tissue led to the development of …

4-Borono-2-[18F] fluoro-D, L-phenylalanine: a possible tracer for melanoma diagnosis with PET

K Ishiwata, T Ido, C Honda, M Kawamura… - International journal of …, 1992 - Elsevier
Abstract The potential of 4-borono-2-[18 F] fluoro-d, l-phenylalanine ([18 F] FBPA), a
fluorinated derivative of a target compound for boron neutron capture therapy, for melanoma …

Positron Emission Tomography/Computed Tomography Transformation of Oncology: Melanoma and Skin Malignancies

ST Lee, N Kovaleva, C Senko, D Kee, AM Scott - PET clinics, 2024 - pet.theclinics.com
Background Skin cancers are the most common of all cancers, with the most aggressive
cutaneous malignancies including malignant melanoma, cutaneous squamous cell …

[PDF][PDF] Carbon-11-methionine PET imaging of malignant melanoma

P Lindholm, S Leskinen, K Någren… - Journal of Nuclear …, 1995 - Soc Nuclear Med
The purpose of the study was to assess the feasibility of PET and L-[methyl-11C] methionine
(11C-methionine) in the detection of malignantmelanomaMethods …

Cellular accumulation of 18F-labelled boronophenylalanine depending on DNA synthesis and melanin incorporation: a double-tracer microautoradiographic study of …

R Kubota, S Yamada, K Ishiwata, M Tada, T Ido… - British journal of …, 1993 - nature.com
The cellular distribution of 4-borono-2-[18F] fluoro-L-phenylalanine ([18F] FBPA, an analog
of p-boronophenylaline), a potential agent for boron neutron capture therapy (BNCT), and [6 …