Specific binding of TES-23 antibody to tumour vascular endothelium in mice, rats and human cancer tissue: a novel drug carrier for cancer targeting therapy

S Tsunoda, I Ohizumi, J Matsui, K Koizumi… - British journal of …, 1999 - nature.com
The tissue distribution of anti-tumour vascular endothelium monoclonal antibody (TES-23)
produced by immunizing with plasma membrane vesicles from isolated rat tumour-derived …

Distribution of 111in‐ and 125i‐labeled monoclonal antibody 17‐1a in mice bearing xenografts of human pancreatic carcinoma hup‐t4

M Maeda, M Shoji, T Kawagoshi, R Futatsuya… - Cancer, 1994 - Wiley Online Library
Background. The prognosis of pancreatic adenocarcinoma still remains poor because of the
lack of reliable diagnostic tests for early stages of the disease. Monoclonal antibody 17‐1A …

A ROBUST SUMMARIZE–REGRESS PROCEDURE FOR TISSUE-SPECIFIC PHARMACOKINETICS

MS Mayo, DJ Buchsbaum - Journal of Biopharmaceutical Statistics, 2000 - Taylor & Francis
The destructive sampling necessary to obtain tissue-specific pharmacokinetics of
radiolabeled ligands does not permit true time-dependent models to be estimated. To adjust …

111In, 125I 標識モノクローナル抗体 17-1A のヒト膵臓癌 HuP-T4 担癌マウスにおける体内動態

前田正敏, 二本松博子, 川腰利之, 庄司美樹… - Radioisotopes, 1992 - jstage.jst.go.jp
抄録 放射性核種標識モノグローナル抗体 (MoAb) 17-1A の生体内動態をヒト膵臓癌 HuP-T4
担癌ヌードマウスについて検討した. MoAb17-1A は, 免疫組織化学的にも HuP-T4 …

[CITATION][C] Monoclonal and engineered antibodies for human parenteral clinical use: regulatory considerations

V Manohar, T Hoffman - Trends in biotechnology, 1992 - Elsevier
Regulation of the use of monoclonal antibodies (mAbs) and their related technologies has
evolved together with their development. The many unique features of antibodies have …