Therapeutic radiopharmaceuticals are radiolabeled molecules designed to deliver
therapeutic doses of ionizing radiation to specific disease sites (1, 2). Therapeutic doses of …

Radiopharmaceuticals, drugs containing a radionu-clide, are used routinely in nuclear
medicine depart-ments for the diagnosis of disease and are under investigation for use in …

Over the last twenty-five years 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid
(DOTA) has made a significant impact on the field of diagnostic imaging. DOTA is not the …

This review summarizes some of the developments of metal complexes and metal-complex-
bioconjugates for the diagnosis of disease states that have occurred over the past 10 years …

Metal complexes of DOTA (1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid)−
peptide conjugates are increasingly used as targeted imaging and therapeutic …

Radioimmunoimaging and therapy has been an area of interest for several decades. Steady
progress has been made toward clinical translation of radiolabeled monoclonal antibodies …

Metallic radionuclides are the mainstay of both diagnostic and therapeutic
radiopharmaceuticals. Therapeutic nuclear medicine is less advanced but has tremendous …

T-cell Bispecific Antibodies (TCBs) elicit anti-tumor responses by cross-linking T-cells to
tumor cells and mediate polyclonal T-cell expansion that is independent of T-cell receptor …

The synthesis of the octadentate bispidine ligand bearing two picolinic acid pendant arms
(H2bispa2), and its coordination chemistry with radionuclides relevant for nuclear medicine …