The colorectaltumor is one ofthe most common tumors in oncology. Abdominoperineal
resection of colorectal carcinoma is followed by local recurrence in 25%-30% of all …

The use of radionuclides in medicine is based largely on the discoveries of two critical
concepts, the “tracer principle” and the “magic bullet”. In 1913, George de Hevesy …

Copper-64 (T 1 2= 12.7 h) is an intermediate-lived positron-emitting radionuclide that is a
useful radiotracer for positron emission tomography (PET) as well as a promising …

Radiopharmaceuticals, drugs containing a radionu-clide, are used routinely in nuclear
medicine depart-ments for the diagnosis of disease and are under investigation for use in …

The chemistry, radiochemistry, radiobiology, and radiopharmacology of
radiopharmaceuticals containing copper radionuclides are reviewed. Copper radionuclides …

The molecules known as bis (thiosemicarbazones) derived from 1, 2-diones can act as
tetradentate ligands for Cu (II), forming stable, neutral complexes. As a family, these …

Copper (II) bis (thiosemicarbazone) complexes labelled with Cu-60/62/64 are useful
radiopharmaceuticals for imaging blood flow and hypoxic tissues in vivo. The aim of this …

Generator-derived radionuclides for PET/CT imaging are promising for optimizing targeted
radiotherapy by an individual patient-based approach, applying pre-therapeutic evaluation …

Late-onset Alzheimer's disease (AD; LOAD) is the most common human neurodegenerative
disease, however, the availability and efficacy of disease-modifying interventions is severely …

Targeted molecular imaging with positron emission tomography (PET) constitutes a
successful technique for detecting and diagnosing disease conditions promptly and …