Lipoproteins and lipoprotein mimetics for imaging and drug delivery
Lipoproteins are a set of natural nanoparticles whose main role is the transport of fats within
the body. While much work has been done to develop synthetic nanocarriers to deliver …
the body. While much work has been done to develop synthetic nanocarriers to deliver …
Modified natural nanoparticles as contrast agents for medical imaging
The development of novel and effective contrast agents is one of the drivers of the ongoing
improvement in medical imaging. Many of the new agents reported are nanoparticle-based …
improvement in medical imaging. Many of the new agents reported are nanoparticle-based …
Radiolabeled liposomes and lipoproteins as lipidic nanoparticles for imaging and therapy
L Aranda-Lara, E Morales-Avila… - Chemistry and Physics …, 2020 - Elsevier
Radiolabeled lipidic nanoparticles, particularly liposomes and lipoproteins, are of great
interest as agents for imaging and therapy, due not only to their peculiar physicochemical …
interest as agents for imaging and therapy, due not only to their peculiar physicochemical …
Imaging atherosclerosis and vulnerable plaque
MM Sadeghi, DK Glover, GM Lanza… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Identifying patients at high risk for an acute cardiovascular event such as myocardial
infarction or stroke and assessing the total atherosclerotic burden are clinically important …
infarction or stroke and assessing the total atherosclerotic burden are clinically important …
High-density lipoprotein–based contrast agents for multimodal imaging of atherosclerosis
T Skajaa, DP Cormode, E Falk… - … , and vascular biology, 2010 - Am Heart Assoc
Lipoproteins, natural nanoparticles, have a well-recognized biological role and are highly
suitable as a platform for delivering imaging agents. The ease with which both the exterior …
suitable as a platform for delivering imaging agents. The ease with which both the exterior …
Molecular and metabolic imaging of atherosclerosis
JR Davies, JH Rudd, PL Weissberg - Journal of Nuclear Medicine, 2004 - Soc Nuclear Med
Atherosclerosis is a systemic disease that affects most major arteries of the body and is the
most common cause of premature death in the western world. It develops slowly and often …
most common cause of premature death in the western world. It develops slowly and often …
2 Clinically useful chelators of tripositive elements
RC Hider, AD Hall - Progress in medicinal chemistry, 1991 - Elsevier
Publisher Summary This chapter discusses the clinically useful chelators of tripositive
elements. The clinical use of chelator molecules has been synonymous with the removal of …
elements. The clinical use of chelator molecules has been synonymous with the removal of …
Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo
S Tsimikas, W Palinski, SE Halpern, DW Yeung… - Journal of Nuclear …, 1999 - Springer
Background Oxidatively modified low-density lipoprotein (LDL) is present in atherosclerotic
but not normal arteries and plays a crucial role in the pathogenesis and adverse …
but not normal arteries and plays a crucial role in the pathogenesis and adverse …
Lipoprotein-related and apolipoprotein-mediated delivery systems for drug targeting and imaging
G Almer, H Mangge, A Zimmer… - Current medicinal …, 2015 - ingentaconnect.com
The integration of lipoprotein-related or apolipoprotein-targeted nanoparticles as
pharmaceutical carriers opens new therapeutic and diagnostic avenues in nanomedicine …
pharmaceutical carriers opens new therapeutic and diagnostic avenues in nanomedicine …
Processing of antibody‐radioisotope conjugates after binding to the surface of tumor cells
M Jules Mattes, GL Griffiths, H Diril, DM Goldenberg… - cancer, 1994 - Wiley Online Library
Background. Previous experiments indicated that most antibodies binding to cell surface
antigens are internalized gradually and degraded within lysosomes, with a half‐life of …
antigens are internalized gradually and degraded within lysosomes, with a half‐life of …