Myocardial blood flow measurement by PET: technical aspects and clinical applications

PA Kaufmann, PG Camici - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
The availability of plastic microspheres labeled with different-emitting isotopes has allowed
the quantification of blood flow in different organs, including the heart (1). In the past 3 …

Ammonia metabolism and hyperammonemic disorders

V Walker - Advances in clinical chemistry, 2014 - Elsevier
Human adults produce around 1000 mmol of ammonia daily. Some is reutilized in
biosynthesis. The remainder is waste and neurotoxic. Eventually most is excreted in urine as …

Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging

GD Hutchins, M Schwaiger, KC Rosenspire… - Journal of the American …, 1990 - Elsevier
Abstract Evaluation of regional myocardial blood flow by conventional scintigraphic
techniques is limited to the qualitative assessment of regional tracer distribution. Dynamic …

[PDF][PDF] Coronary flow and flow reserve by PET simplified for clinical applications using rubidium-82 or nitrogen-13-ammonia

K Yoshida, N Mullani, KL Gould - Journal of Nuclear Medicine, 1996 - Soc Nuclear Med
Vxurrent pharmacologie or stress perfusion imaging reflects relative distribution of maximum
coronary flow or relative coronary flow reserve (CFR)(1, 2) which may be normal in the …

A model of blood-ammonia homeostasis based on a quantitative analysis of nitrogen metabolism in the multiple organs involved in the production, catabolism, and …

DG Levitt, MD Levitt - Clinical and experimental gastroenterology, 2018 - Taylor & Francis
Increased blood ammonia (NH3) is an important causative factor in hepatic encephalopathy,
and clinical treatment of hepatic encephalopathy is focused on lowering NH3. Ammonia is a …

[PDF][PDF] Validation of nitrogen-13-ammonia tracer kinetic model for quantification of myocardial blood flow using PET

O Muzik, RSB Beanlands, GD Hutchins… - Journal of Nuclear …, 1993 - Soc Nuclear Med
The purpose of this study was to validate the three compartment kinetic model for myocardial
blood flow measurements using †3N-ammoniadeveloped at our insti tution. Blood flow …

Quantification of regional myocardial blood flow using 13N-ammonia and reoriented dynamic positron emission tomographic imaging.

WG Kuhle, G Porenta, SC Huang, D Buxton… - Circulation, 1992 - Am Heart Assoc
BACKGROUND Regional myocardial blood flow has been quantified using transaxial
positron emission tomographic (PET) imaging and tracer kinetic modeling. However, the use …

Evidence for regional catecholamine uptake and storage sites in the transplanted human heart by positron emission tomography.

M Schwaiger, GD Hutchins, V Kalff… - The Journal of …, 1991 - Am Soc Clin Investig
Positron emission tomography in combination with the newly introduced catecholamine
analogue [11C] hydroxyephedrine ([11C] HED) enables the noninvasive delineation of …

Comparison of maximal myocardial blood flow during adenosine infusion with that of intravenous dipyridamole in normal men

SY Chan, RC Brunken, J Czernin, G Porenta… - Journal of the American …, 1992 - Elsevier
Objective. This study compared quantitatively the efficacy of intravenous adenosine and
dipyridamole for pharmacologic induction of myocardial hyperemia. Background …

[1-11C] Acetate as a quantitative perfusion tracer in myocardial PET

J van den Hoff, W Burchert, AR Börner… - Journal of Nuclear …, 2001 - Soc Nuclear Med
Our objective was to investigate the properties of [1-11C] acetate as a quantitative perfusion
tracer for myocardial PET studies. Methods: We determined the flow dependence of the …