Synthesis of 11C, 18F, 15O, and 13N Radiolabels for Positron Emission Tomography

PW Miller, NJ Long, R Vilar… - Angewandte Chemie …, 2008 - Wiley Online Library
Positron emission tomography (PET) is a powerful and rapidly developing area of molecular
imaging that is used to study and visualize human physiology by the detection of positron …

Positron-emission tomography and assessment of cancer therapy

ME Juweid, BD Cheson - New England Journal of Medicine, 2006 - Mass Medical Soc
Positron-Emission Tomography and Assessment of Cancer Therapy | NEJM Skip to main content
NEJM Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

Conjugated photosensitizers for imaging and PDT in cancer research

JCS Simões, S Sarpaki… - Journal of medicinal …, 2020 - ACS Publications
Early cancer detection and perfect understanding of the disease are imperative toward
efficient treatments. It is straightforward that, for choosing a specific cancer treatment …

Molecular imaging of hypoxia

KA Krohn, JM Link, RP Mason - Journal of Nuclear Medicine, 2008 - Soc Nuclear Med
Hypoxia, a condition of insufficient O 2 to support metabolism, occurs when the vascular
supply is interrupted, as in stroke or myocardial infarction, or when a tumor outgrows its …

Quantifying regional hypoxia in human tumors with positron emission tomography of [18F] fluoromisonidazole: a pretherapy study of 37 patients

JS Rasey, W Koh, ML Evans, LM Peterson… - International Journal of …, 1996 - Elsevier
Purpose: To assess pretreatment hypoxia in a variety of tumors using positron emission
tomography (PET) after injection of the hypoxia-binding radiopharmaceutical [“'F] …

Imaging of hypoxia in human tumors with [F-18] fluoromisonidazole

WJ Koh, JS Rasey, ML Evans, JR Grierson… - International Journal of …, 1992 - Elsevier
Fluoromisonidazole (FMISO) has been shown to bind selectively to hypoxic cells in vitro and
in vivo at radiobiologically significant oxygen levels. When labeled with the positron emitter …

Chemistry with [18F]Fluoride Ion

L Cai, S Lu, VW Pike - European Journal of Organic Chemistry, 2008 - Wiley Online Library
The success of molecular imaging with positron‐emission tomography (PET) depends on
the availability of selective molecular probes labeled with positron‐emitters, such asfluorine …

[HTML][HTML] PET radiopharmaceuticals for imaging of tumor hypoxia: a review of the evidence

E Lopci, I Grassi, A Chiti, C Nanni… - American journal of …, 2014 - ncbi.nlm.nih.gov
Hypoxia is a pathological condition arising in living tissues when oxygen supply does not
adequately cover the cellular metabolic demand. Detection of this phenomenon in tumors is …

Nitroimidazoles and imaging hypoxia

A Nunn, K Linder, HW Strauss - European journal of nuclear medicine, 1995 - Springer
Decreased tissue oxygen tension is a component of many diseases. Although hypoxia can
be secondary to a low inspired P0 2 or a variety of lung disorders, the commonest cause is …

Hypoxia and Glucose Metabolism in Malignant Tumors: Evaluation by [18F]Fluoromisonidazole and [18F]Fluorodeoxyglucose Positron Emission Tomography …

JG Rajendran, DA Mankoff, F O'Sullivan… - Clinical cancer …, 2004 - AACR
Purpose: The aim of this study is to compare glucose metabolism and hypoxia in four
different tumor types using positron emission tomography (PET). 18F-labeled …