Gallium, a semi-metallic element in group 13 (IIIa) of the periodic table, has shown efficacy
in the treatment of several apparently diverse disorders. These disorders can be broadly …

A review of the literature was conducted to study the pathomechanics by which Paget's
Disease of bone (PD) alters the spinal structures that result in distinct spinal pathologic …

Gallium nitrate has been used clinically to treat cancer-related hypercalcemia. It has been
suggested that gallium may reduce calcium release from bone by inhibiting bone resorption …

The effects of gallium nitrate on bone turnover were evaluated in four patients with active
Paget's disease. Treatment with gallium nitrate (100 mg/m 2 daily for 5 days, intravenously in …

Objective: To evaluate whether a brief course of treatment with gallium nitrate can reduce
biochemical parameters of accelerated bone turnover in patients with advanced Paget …

Gallium salts have been explored for their applicability as antineoplastic drugs for more than
two decades, but clinical experience has revealed unfavorable pharmacokinetic and …

Fibrous dysplasia of bone is an uncommon congenital skeletal disorder that is found equally
in both sexes and is not inherited. It probably first appeared in the medical literature in 1891 …

Paget's disease of bone is a focal disorder of unknown etiology characterized initially by
excessive resorption and subsequently by excessive formation of bone, culminating in a …

Gallium nitrate, a drug that inhibits calcium release from bone, has been proven a safe and
effective treatment for the accelerated bone resorption associated with cancer. Though bone …

Two N-substituted 3-hydroxy-4-pyridinones (1-(3′-aminopropyl)-3-hydroxy-2-methyl-4-
pyridinone (L1) and 1-(2′-carboxyethyl)-3-hydroxy-2-methyl-4-pyridinone (L2)) were …