Many recent reports have demonstrated that rapid uptake of liposomes in vivo by cells of the
mononuclear phagocytic systcm (MPS), which has restricted their therapeutic utility, can be …

Liposomes have been extensively studied and are used in the treatment of several
diseases. Liposomes improve the therapeutic efficacy by enhancing drug absorption while …

In preclinical studies, a doxorubicin liposome formulation containing polyethylene-glycol
(Doxil) shows a long circulation time in plasma, enhanced accumulation in murine tumors …

The recent developments of nuclear medicine in oncology have involved numerous
investigations of novel specific tumor-targeting radiopharmaceuticals as a major area of …

Efforts to overcome rapid uptake of liposomes by cells of the mononuclear phagocytic
system (MPS) have identified that lipids derivatized with the hydrophilic polymer poly …

The pharmacokinetics and biodistribution of liposome-encapsulated drugs are controlled by
the interplay of two variables: the rate of plasma clearance of the liposome carrier, and the …

In recent years the importance of molecular and diagnostic imaging has increased
dramatically in the treatment planning of many diseases and in particular in cancer therapy …

We have examined the distribution of radiolabeled liposomes in tumor-bearing mice after iv
injection. Two mouse tumors (B16 melanoma, J6456 lymphoma) and a human tumor …

A strategy to target functionalized quantum dot− liposome (f-QD-L) hybrid vesicles in the
solid tumor tissue of tumor-bearing mice is explored. Functionalized polyethylene glycol …

Radiolabeling of liposomes with 64Cu (t 1/2= 12.7 h) is attractive for molecular imaging and
monitoring drug delivery. A simple chelation procedure, performed at a low temperature and …